Identity
HGNC
LOCATION
19p13.11
LOCUSID
ALIAS
ANKRD41,LEM3,LEMD6
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 126549
HGNC: 26812
Ensembl: ENSG00000160117
Variants:
dbSNP: 126549
ClinVar: 126549
TCGA: ENSG00000160117
COSMIC: ANKLE1
RNA/Proteins
Expression (GTEx)
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36825683 | 2023 | Human Endonuclease ANKLE1 Localizes at the Midbody and Processes Chromatin Bridges to Prevent DNA Damage and cGAS-STING Activation. | 6 |
| 37076474 | 2023 | Dephosphocholination by Legionella effector Lem3 functions through remodelling of the switch II region of Rab1b. | 0 |
| 37216589 | 2023 | Biochemical and mechanistic analysis of the cleavage of branched DNA by human ANKLE1. | 0 |
| 36825683 | 2023 | Human Endonuclease ANKLE1 Localizes at the Midbody and Processes Chromatin Bridges to Prevent DNA Damage and cGAS-STING Activation. | 6 |
| 37076474 | 2023 | Dephosphocholination by Legionella effector Lem3 functions through remodelling of the switch II region of Rab1b. | 0 |
| 37216589 | 2023 | Biochemical and mechanistic analysis of the cleavage of branched DNA by human ANKLE1. | 0 |
| 33927264 | 2021 | Investigation of triple-negative breast cancer risk alleles in an International African-enriched cohort. | 6 |
| 33927264 | 2021 | Investigation of triple-negative breast cancer risk alleles in an International African-enriched cohort. | 6 |
| 31509622 | 2020 | ANKLE1 N(6) -Methyladenosine-related variant is associated with colorectal cancer risk by maintaining the genomic stability. | 28 |
| 32866453 | 2020 | Human ANKLE1 Is a Nuclease Specific for Branched DNA. | 0 |
| 31509622 | 2020 | ANKLE1 N(6) -Methyladenosine-related variant is associated with colorectal cancer risk by maintaining the genomic stability. | 28 |
| 32866453 | 2020 | Human ANKLE1 Is a Nuclease Specific for Branched DNA. | 0 |
| 28362817 | 2017 | Cis-eQTL-based trans-ethnic meta-analysis reveals novel genes associated with breast cancer risk. | 38 |
| 28957321 | 2017 | Identification of breast cancer associated variants that modulate transcription factor binding. | 25 |
| 28362817 | 2017 | Cis-eQTL-based trans-ethnic meta-analysis reveals novel genes associated with breast cancer risk. | 38 |
Citation
Dessen P
ANKLE1 (ankyrin repeat and LEM domain containing 1)
Atlas Genet Cytogenet Oncol Haematol. 2016-12-01
Online version: http://atlasgeneticsoncology.org/gene/56679/ankle1-(ankyrin-repeat-and-lem-domain-containing-1)
