Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 2314
MIM: 600362
HGNC: 3750
Ensembl: ENSG00000177731
Variants:
dbSNP: 2314
ClinVar: 2314
TCGA: ENSG00000177731
COSMIC: FLII
RNA/Proteins
Expression (GTEx)
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37126682 | 2023 | A human FLII gene variant alters sarcomeric actin thin filament length and predisposes to cardiomyopathy. | 3 |
| 37126682 | 2023 | A human FLII gene variant alters sarcomeric actin thin filament length and predisposes to cardiomyopathy. | 3 |
| 32643295 | 2021 | Role of the small GTPase activating protein IQGAP1 in collagen phagocytosis. | 2 |
| 34011528 | 2021 | Flightless I Homolog Reverses Enzalutamide Resistance through PD-L1-Mediated Immune Evasion in Prostate Cancer. | 10 |
| 34698116 | 2021 | FLII and MLL1 Cooperatively Regulate Aryl Hydrocarbon Receptor-Mediated Transcription in ARPE-19 Cells. | 0 |
| 34948000 | 2021 | Increased Expression of Flightless I in Cutaneous Squamous Cell Carcinoma Affects Wnt/β-Catenin Signaling Pathway. | 0 |
| 32643295 | 2021 | Role of the small GTPase activating protein IQGAP1 in collagen phagocytosis. | 2 |
| 34011528 | 2021 | Flightless I Homolog Reverses Enzalutamide Resistance through PD-L1-Mediated Immune Evasion in Prostate Cancer. | 10 |
| 34698116 | 2021 | FLII and MLL1 Cooperatively Regulate Aryl Hydrocarbon Receptor-Mediated Transcription in ARPE-19 Cells. | 0 |
| 34948000 | 2021 | Increased Expression of Flightless I in Cutaneous Squamous Cell Carcinoma Affects Wnt/β-Catenin Signaling Pathway. | 0 |
| 31614010 | 2020 | Flightless I, a contributing factor to skin blistering in Kindler syndrome patients? | 2 |
| 32504039 | 2020 | Flightless-1 inhibits ER stress-induced apoptosis in colorectal cancer cells by regulating Ca(2+) homeostasis. | 11 |
| 32764293 | 2020 | Attenuation of Flightless I Increases Human Pericyte Proliferation, Migration and Angiogenic Functions and Improves Healing in Murine Diabetic Wounds. | 9 |
| 32854733 | 2020 | Increasing the level of cytoskeletal protein Flightless I reduces adhesion formation in a murine digital flexor tendon model. | 4 |
| 31614010 | 2020 | Flightless I, a contributing factor to skin blistering in Kindler syndrome patients? | 2 |
Citation
Dessen P
FLII (FLII actin remodeling protein)
Atlas Genet Cytogenet Oncol Haematol. 2017-01-01
Online version: http://atlasgeneticsoncology.org/gene/56692/flii-(flii-actin-remodeling-protein)
