NIFK (nucleolar protein interacting with the FHA domain of MKI67)

2017-01-01  

Identity

HGNC
LOCATION
2q14.3
LOCUSID
ALIAS
MKI67IP,Nopp34
FUSION GENES

Other Information

Locus ID:

NCBI: 84365
MIM: 611970
HGNC: 17838
Ensembl: ENSG00000155438

Variants:

dbSNP: 84365
ClinVar: 84365
TCGA: ENSG00000155438
COSMIC: NIFK

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000155438ENST00000285814Q9BYG3
ENSG00000155438ENST00000423105H7BZL0
ENSG00000155438ENST00000447132C9J808
ENSG00000155438ENST00000451734C9J6C5

Expression (GTEx)

0
10
20
30
40
50
60
70
80

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
378007822023NIFK as a potential prognostic biomarker in colorectal cancer correlating with immune infiltrates.1
378007822023NIFK as a potential prognostic biomarker in colorectal cancer correlating with immune infiltrates.1
269842802016The nucleolar protein NIFK promotes cancer progression via CK1α/β-catenin in metastasis and Ki-67-dependent cell proliferation.21
269842802016The nucleolar protein NIFK promotes cancer progression via CK1α/β-catenin in metastasis and Ki-67-dependent cell proliferation.21
258266592015The RNA recognition motif of NIFK is required for rRNA maturation during cell cycle progression.17
258266592015The RNA recognition motif of NIFK is required for rRNA maturation during cell cycle progression.17
215397732011Direct observations of shifts in the β-sheet register of a protein-peptide complex using explicit solvent simulations.5
215397732011Direct observations of shifts in the β-sheet register of a protein-peptide complex using explicit solvent simulations.5
146597642004Structure of human Ki67 FHA domain and its binding to a phosphoprotein fragment from hNIFK reveal unique recognition sites and new views to the structural basis of FHA domain functions.17
146597642004Structure of human Ki67 FHA domain and its binding to a phosphoprotein fragment from hNIFK reveal unique recognition sites and new views to the structural basis of FHA domain functions.17

Citation

Dessen P

NIFK (nucleolar protein interacting with the FHA domain of MKI67)

Atlas Genet Cytogenet Oncol Haematol. 2017-01-01

Online version: http://atlasgeneticsoncology.org/gene/56695/nifk-(nucleolar-protein-interacting-with-the-fha-domain-of-mki67)