Identity
HGNC
LOCATION
Xq22.3
LOCUSID
ALIAS
FXY2,MRX101,RNF60,TRIM1
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 11043
MIM: 300204
HGNC: 7096
Ensembl: ENSG00000080561
Variants:
dbSNP: 11043
ClinVar: 11043
TCGA: ENSG00000080561
COSMIC: MID2
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000080561 | ENST00000262843 | Q9UJV3 |
| ENSG00000080561 | ENST00000443968 | Q9UJV3 |
| ENSG00000080561 | ENST00000451923 | A6PVI4 |
Expression (GTEx)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38467738 | 2024 | Expanding the genetic and phenotypic spectrum of TRAPPC9 and MID2-related neurodevelopmental disabilities: report of two novel mutations, 3D-modelling, and molecular docking studies. | 0 |
| 38467738 | 2024 | Expanding the genetic and phenotypic spectrum of TRAPPC9 and MID2-related neurodevelopmental disabilities: report of two novel mutations, 3D-modelling, and molecular docking studies. | 0 |
| 35266954 | 2022 | The E3 ligase TRIM1 ubiquitinates LRRK2 and controls its localization, degradation, and toxicity. | 7 |
| 35266954 | 2022 | The E3 ligase TRIM1 ubiquitinates LRRK2 and controls its localization, degradation, and toxicity. | 7 |
| 26748699 | 2016 | The X-Linked-Intellectual-Disability-Associated Ubiquitin Ligase Mid2 Interacts with Astrin and Regulates Astrin Levels to Promote Cell Division. | 18 |
| 26791755 | 2016 | Midline2 is overexpressed and a prognostic indicator in human breast cancer and promotes breast cancer cell proliferation in vitro and in vivo. | 10 |
| 26748699 | 2016 | The X-Linked-Intellectual-Disability-Associated Ubiquitin Ligase Mid2 Interacts with Astrin and Regulates Astrin Levels to Promote Cell Division. | 18 |
| 26791755 | 2016 | Midline2 is overexpressed and a prognostic indicator in human breast cancer and promotes breast cancer cell proliferation in vitro and in vivo. | 10 |
| 24115387 | 2014 | Targeted deep resequencing identifies MID2 mutation for X-linked intellectual disability with varied disease severity in a large kindred from India. | 24 |
| 24115387 | 2014 | Targeted deep resequencing identifies MID2 mutation for X-linked intellectual disability with varied disease severity in a large kindred from India. | 24 |
| 16283679 | 2005 | An Xq22.3 duplication detected by comparative genomic hybridization microarray (Array-CGH) defines a new locus (FGS5) for FG syndrome. | 10 |
| 16283679 | 2005 | An Xq22.3 duplication detected by comparative genomic hybridization microarray (Array-CGH) defines a new locus (FGS5) for FG syndrome. | 10 |
| 11806752 | 2002 | MID1 and MID2 homo- and heterodimerise to tether the rapamycin-sensitive PP2A regulatory subunit, alpha 4, to microtubules: implications for the clinical variability of X-linked Opitz GBBB syndrome and other developmental disorders. | 39 |
| 11806752 | 2002 | MID1 and MID2 homo- and heterodimerise to tether the rapamycin-sensitive PP2A regulatory subunit, alpha 4, to microtubules: implications for the clinical variability of X-linked Opitz GBBB syndrome and other developmental disorders. | 39 |
Citation
Dessen P
MID2 (midline 2)
Atlas Genet Cytogenet Oncol Haematol. 2017-01-01
Online version: http://atlasgeneticsoncology.org/gene/56701/mid2-(midline-2)
