Identity
HGNC
LOCATION
14q22.2
LOCUSID
ALIAS
AND-1,AND1,CHTF4,CTF4
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 11169
MIM: 608126
HGNC: 23170
Ensembl: ENSG00000198554
Variants:
dbSNP: 11169
ClinVar: 11169
TCGA: ENSG00000198554
COSMIC: WDHD1
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000198554 | ENST00000360586 | O75717 |
| ENSG00000198554 | ENST00000420358 | O75717 |
| ENSG00000198554 | ENST00000455555 | C9JYB3 |
| ENSG00000198554 | ENST00000567693 | H3BSQ1 |
Expression (GTEx)
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38654107 | 2024 | ZBTB16 inhibits DNA replication and induces cell cycle arrest by targeting WDHD1 transcription in lung adenocarcinoma. | 0 |
| 38654107 | 2024 | ZBTB16 inhibits DNA replication and induces cell cycle arrest by targeting WDHD1 transcription in lung adenocarcinoma. | 0 |
| 34999279 | 2022 | The clinical significance of transcription factor WD repeat and HMG-box DNA binding protein 1 in laryngeal squamous cell carcinoma and its potential molecular mechanism. | 6 |
| 35065237 | 2022 | Targeted inhibition of acidic nucleoplasmic DNA-binding protein 1 enhances radiosensitivity of non-small cell lung cancer. | 7 |
| 34999279 | 2022 | The clinical significance of transcription factor WD repeat and HMG-box DNA binding protein 1 in laryngeal squamous cell carcinoma and its potential molecular mechanism. | 6 |
| 35065237 | 2022 | Targeted inhibition of acidic nucleoplasmic DNA-binding protein 1 enhances radiosensitivity of non-small cell lung cancer. | 7 |
| 32883234 | 2020 | WDHD1 facilitates G1 checkpoint abrogation in HPV E7 expressing cells by modulating GCN5. | 7 |
| 33221821 | 2020 | WDHD1 is essential for the survival of PTEN-inactive triple-negative breast cancer. | 13 |
| 32883234 | 2020 | WDHD1 facilitates G1 checkpoint abrogation in HPV E7 expressing cells by modulating GCN5. | 7 |
| 33221821 | 2020 | WDHD1 is essential for the survival of PTEN-inactive triple-negative breast cancer. | 13 |
| 30314946 | 2019 | MicroRNA-494-dependent WDHDI inhibition suppresses epithelial-mesenchymal transition, tumor growth and metastasis in cholangiocarcinoma. | 16 |
| 30314946 | 2019 | MicroRNA-494-dependent WDHDI inhibition suppresses epithelial-mesenchymal transition, tumor growth and metastasis in cholangiocarcinoma. | 16 |
| 30082684 | 2018 | AND-1 fork protection function prevents fork resection and is essential for proliferation. | 28 |
| 30082684 | 2018 | AND-1 fork protection function prevents fork resection and is essential for proliferation. | 28 |
| 27940552 | 2017 | And-1 coordinates with CtIP for efficient homologous recombination and DNA damage checkpoint maintenance. | 19 |
Citation
Dessen P
WDHD1 (WD repeat and HMG-box DNA binding protein 1)
Atlas Genet Cytogenet Oncol Haematol. 2017-01-01
Online version: http://atlasgeneticsoncology.org/gene/56704/wdhd1-(wd-repeat-and-hmg-box-dna-binding-protein-1)
