Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 139341
MIM: 300871
HGNC: 28746
Ensembl: ENSG00000069509
Variants:
dbSNP: 139341
ClinVar: 139341
TCGA: ENSG00000069509
COSMIC: FUNDC1
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000069509 | ENST00000378045 | Q8IVP5 |
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Mitophagy - animal | KEGG | ko04137 |
| Mitophagy - animal | KEGG | hsa04137 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36828120 | 2024 | FUNDC1 interacts with GPx4 to govern hepatic ferroptosis and fibrotic injury through a mitophagy-dependent manner. | 13 |
| 37691112 | 2024 | Neutrophil extracellular traps aggravate intestinal epithelial necroptosis in ischaemia-reperfusion by regulating TLR4/RIPK3/FUNDC1-required mitophagy. | 5 |
| 38411432 | 2024 | [FUNDC1 promotes the formation of MAMs involved in angiogenesis]. | 0 |
| 38584135 | 2024 | Mitophagy mediated by HIF-1α/FUNDC1 signaling in tubular cells protects against renal ischemia/reperfusion injury. | 0 |
| 36828120 | 2024 | FUNDC1 interacts with GPx4 to govern hepatic ferroptosis and fibrotic injury through a mitophagy-dependent manner. | 13 |
| 37691112 | 2024 | Neutrophil extracellular traps aggravate intestinal epithelial necroptosis in ischaemia-reperfusion by regulating TLR4/RIPK3/FUNDC1-required mitophagy. | 5 |
| 38411432 | 2024 | [FUNDC1 promotes the formation of MAMs involved in angiogenesis]. | 0 |
| 38584135 | 2024 | Mitophagy mediated by HIF-1α/FUNDC1 signaling in tubular cells protects against renal ischemia/reperfusion injury. | 0 |
| 37298100 | 2023 | FUNDC1: An Emerging Mitochondrial and MAMs Protein for Mitochondrial Quality Control in Heart Diseases. | 2 |
| 37951930 | 2023 | Integration of FUNDC1-associated mitochondrial protein import and mitochondrial quality control contributes to TDP-43 degradation. | 1 |
| 37298100 | 2023 | FUNDC1: An Emerging Mitochondrial and MAMs Protein for Mitochondrial Quality Control in Heart Diseases. | 2 |
| 37951930 | 2023 | Integration of FUNDC1-associated mitochondrial protein import and mitochondrial quality control contributes to TDP-43 degradation. | 1 |
| 34699308 | 2022 | Increased FUN14 domain containing 1 (FUNDC1) ubiquitination level inhibits mitophagy and alleviates the injury in hypoxia-induced trophoblast cells. | 5 |
| 34906568 | 2022 | CircFUNDC1 knockdown alleviates oxygen-glucose deprivation-induced human brain microvascular endothelial cell injuries by inhibiting PTEN via miR-375. | 6 |
| 35179404 | 2022 | FUNDC1 Induces Apoptosis and Autophagy Under Oxidative Stress via PI3K/Akt/mTOR Pathway in Cataract Lens Cells. | 9 |
Citation
Dessen P
FUNDC1 (FUN14 domain containing 1)
Atlas Genet Cytogenet Oncol Haematol. 2017-01-01
Online version: http://atlasgeneticsoncology.org/gene/56706/fundc1-(fun14-domain-containing-1)
