Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 157285
MIM: 617344
HGNC: 25438
Ensembl: ENSG00000275342
Variants:
dbSNP: 157285
ClinVar: 157285
TCGA: ENSG00000275342
COSMIC: PRAG1
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000275342 | ENST00000615670 | Q86YV5 |
| ENSG00000275342 | ENST00000622241 | Q86YV5 |
Expression (GTEx)
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37958966 | 2023 | Candidate Genes for IgA Nephropathy in Pediatric Patients: Exome-Wide Association Study. | 0 |
| 37958966 | 2023 | Candidate Genes for IgA Nephropathy in Pediatric Patients: Exome-Wide Association Study. | 0 |
| 35059869 | 2022 | The inhibition of Panc1 cancer cells invasion by hAMSCs secretome through suppression of tyrosine phosphorylation of SGK223 (at Y411 site), c-Src (at Y416, Y530 sites), AKT activity, and JAK1/Stat3 signaling. | 2 |
| 35059869 | 2022 | The inhibition of Panc1 cancer cells invasion by hAMSCs secretome through suppression of tyrosine phosphorylation of SGK223 (at Y411 site), c-Src (at Y416, Y530 sites), AKT activity, and JAK1/Stat3 signaling. | 2 |
| 29503074 | 2018 | Dimerization of the Pragmin Pseudo-Kinase Regulates Protein Tyrosine Phosphorylation. | 21 |
| 29503074 | 2018 | Dimerization of the Pragmin Pseudo-Kinase Regulates Protein Tyrosine Phosphorylation. | 21 |
| 29079850 | 2017 | Structure of SgK223 pseudokinase reveals novel mechanisms of homotypic and heterotypic association. | 21 |
| 29079850 | 2017 | Structure of SgK223 pseudokinase reveals novel mechanisms of homotypic and heterotypic association. | 21 |
| 26782286 | 2016 | Silencing NACK by siRNA inhibits tumorigenesis in non-small cell lung cancer via targeting Notch1 signaling pathway. | 9 |
| 27116701 | 2016 | C-terminal Src kinase-mediated EPIYA phosphorylation of Pragmin creates a feed-forward C-terminal Src kinase activation loop that promotes cell motility. | 17 |
| 27531744 | 2016 | Homo- and Heterotypic Association Regulates Signaling by the SgK269/PEAK1 and SgK223 Pseudokinases. | 13 |
| 26782286 | 2016 | Silencing NACK by siRNA inhibits tumorigenesis in non-small cell lung cancer via targeting Notch1 signaling pathway. | 9 |
| 27116701 | 2016 | C-terminal Src kinase-mediated EPIYA phosphorylation of Pragmin creates a feed-forward C-terminal Src kinase activation loop that promotes cell motility. | 17 |
| 27531744 | 2016 | Homo- and Heterotypic Association Regulates Signaling by the SgK269/PEAK1 and SgK223 Pseudokinases. | 13 |
| 26215634 | 2015 | The pseudokinase SgK223 promotes invasion of pancreatic ductal epithelial cells through JAK1/Stat3 signaling. | 24 |
Citation
Dessen P
PRAG1 (PEAK1 related, kinase-activating pseudokinase 1)
Atlas Genet Cytogenet Oncol Haematol. 2017-01-01
Online version: http://atlasgeneticsoncology.org/gene/56711/prag1-(peak1-related-kinase-activating-pseudokinase-1)
