CAVIN3 (caveolae associated protein 3)

2017-04-01  

Identity

HGNC
LOCATION
11p15.4
LOCUSID
ALIAS
HSRBC,PRKCDBP,SRBC,cavin-3

Other Information

Locus ID:

NCBI: 112464
MIM: 618303
HGNC: 9400
Ensembl: ENSG00000170955

Variants:

dbSNP: 112464
ClinVar: 112464
TCGA: ENSG00000170955
COSMIC: CAVIN3

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000170955ENST00000303927Q969G5
ENSG00000170955ENST00000530979E9PIE3

Protein levels (Protein atlas)

Not detected
Low
Medium
High

PharmGKB

Entity IDNameTypeEvidenceAssociationPKPDPMIDs
PA39ADRB2GenePathwayassociated

References

Pubmed IDYearTitleCitations
352249602022PRKCDBP Methylation is a Potential and Promising Candidate Biomarker for Non-small Cell Lung Cancer.1
352249602022PRKCDBP Methylation is a Potential and Promising Candidate Biomarker for Non-small Cell Lung Cancer.1
341426592021Cavin3 released from caveolae interacts with BRCA1 to regulate the cellular stress response.7
341426592021Cavin3 released from caveolae interacts with BRCA1 to regulate the cellular stress response.7
326768142020Contribution of DNA methylation and EZH2 in SRBC down-regulation in gastric cancer.5
328625982020Matrine induces apoptosis and autophagy in human lung adenocarcinoma cells via upregulation of Cavin3 and suppression of PI3K/AKT pathway.4
329455032020Low expression of PRKCDBP promoted cisplatin resistance in lung adenocarcinoma by DNMT1 and TNF‑α.5
326768142020Contribution of DNA methylation and EZH2 in SRBC down-regulation in gastric cancer.5
328625982020Matrine induces apoptosis and autophagy in human lung adenocarcinoma cells via upregulation of Cavin3 and suppression of PI3K/AKT pathway.4
329455032020Low expression of PRKCDBP promoted cisplatin resistance in lung adenocarcinoma by DNMT1 and TNF‑α.5
308946822019ROR1-CAVIN3 interaction required for caveolae-dependent endocytosis and pro-survival signaling in lung adenocarcinoma.8
313321682019Identification of intracellular cavin target proteins reveals cavin-PP1alpha interactions regulate apoptosis.26
308946822019ROR1-CAVIN3 interaction required for caveolae-dependent endocytosis and pro-survival signaling in lung adenocarcinoma.8
313321682019Identification of intracellular cavin target proteins reveals cavin-PP1alpha interactions regulate apoptosis.26
277211872017PRKCDBP (CAVIN3) and CRY2 associate with major depressive disorder.9

Citation

Dessen P

CAVIN3 (caveolae associated protein 3)

Atlas Genet Cytogenet Oncol Haematol. 2017-04-01

Online version: http://atlasgeneticsoncology.org/gene/56723/cavin3-(caveolae-associated-protein-3)