Identity
HGNC
LOCATION
16p13.3
LOCUSID
ALIAS
SDOS,TIRR
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 84309
MIM: 617338
HGNC: 28154
Ensembl: ENSG00000168101
Variants:
dbSNP: 84309
ClinVar: 84309
TCGA: ENSG00000168101
COSMIC: NUDT16L1
RNA/Proteins
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Proteoglycans in cancer | KEGG | hsa05205 |
| Proteoglycans in cancer | KEGG | ko05205 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 33961797 | 2021 | TIRR inhibits the 53BP1-p53 complex to alter cell-fate programs. | 12 |
| 33961797 | 2021 | TIRR inhibits the 53BP1-p53 complex to alter cell-fate programs. | 12 |
| 29844495 | 2018 | Structural basis for recognition of 53BP1 tandem Tudor domain by TIRR. | 22 |
| 29967538 | 2018 | Mechanism of 53BP1 activity regulation by RNA-binding TIRR and a designer protein. | 18 |
| 30002377 | 2018 | Molecular basis for the inhibition of the methyl-lysine binding function of 53BP1 by TIRR. | 13 |
| 30260431 | 2018 | Protein Syndesmos is a novel RNA-binding protein that regulates primary cilia formation. | 12 |
| 29844495 | 2018 | Structural basis for recognition of 53BP1 tandem Tudor domain by TIRR. | 22 |
| 29967538 | 2018 | Mechanism of 53BP1 activity regulation by RNA-binding TIRR and a designer protein. | 18 |
| 30002377 | 2018 | Molecular basis for the inhibition of the methyl-lysine binding function of 53BP1 by TIRR. | 13 |
| 30260431 | 2018 | Protein Syndesmos is a novel RNA-binding protein that regulates primary cilia formation. | 12 |
| 28213517 | 2017 | The p53-binding protein 1-Tudor-interacting repair regulator complex participates in the DNA damage response. | 28 |
| 28241136 | 2017 | TIRR regulates 53BP1 by masking its histone methyl-lysine binding function. | 66 |
| 28213517 | 2017 | The p53-binding protein 1-Tudor-interacting repair regulator complex participates in the DNA damage response. | 28 |
| 28241136 | 2017 | TIRR regulates 53BP1 by masking its histone methyl-lysine binding function. | 66 |
Citation
Dessen P
NUDT16L1 (nudix hydrolase 16 like 1)
Atlas Genet Cytogenet Oncol Haematol. 2017-04-01
Online version: http://atlasgeneticsoncology.org/gene/56734/nudt16l1-(nudix-hydrolase-16-like-1)
