Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 343035
MIM: 180040
HGNC: 19689
Ensembl: ENSG00000198570
Variants:
dbSNP: 343035
ClinVar: 343035
TCGA: ENSG00000198570
COSMIC: RD3
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000198570 | ENST00000367002 | Q7Z3Z2 |
Expression (GTEx)
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 32493772 | 2020 | Two clusters of surface-exposed amino acid residues enable high-affinity binding of retinal degeneration-3 (RD3) protein to retinal guanylyl cyclase. | 4 |
| 32493772 | 2020 | Two clusters of surface-exposed amino acid residues enable high-affinity binding of retinal degeneration-3 (RD3) protein to retinal guanylyl cyclase. | 4 |
| 30559291 | 2019 | Retinal degeneration 3 (RD3) protein, a retinal guanylyl cyclase regulator, forms a monomeric and elongated four-helix bundle. | 10 |
| 30559291 | 2019 | Retinal degeneration 3 (RD3) protein, a retinal guanylyl cyclase regulator, forms a monomeric and elongated four-helix bundle. | 10 |
| 29030614 | 2017 | Retinal Degeneration Protein 3 (RD3) in normal human tissues: Novel insights. | 5 |
| 29030614 | 2017 | Retinal Degeneration Protein 3 (RD3) in normal human tissues: Novel insights. | 5 |
| 26375249 | 2015 | RD3 loss dictates high-risk aggressive neuroblastoma and poor clinical outcomes. | 10 |
| 26375249 | 2015 | RD3 loss dictates high-risk aggressive neuroblastoma and poor clinical outcomes. | 10 |
| 23308101 | 2013 | Union makes strength: a worldwide collaborative genetic and clinical study to provide a comprehensive survey of RD3 mutations and delineate the associated phenotype. | 11 |
| 23308101 | 2013 | Union makes strength: a worldwide collaborative genetic and clinical study to provide a comprehensive survey of RD3 mutations and delineate the associated phenotype. | 11 |
| 22531706 | 2012 | Mutations in RD3 are associated with an extremely rare and severe form of early onset retinal dystrophy. | 15 |
| 22531706 | 2012 | Mutations in RD3 are associated with an extremely rare and severe form of early onset retinal dystrophy. | 15 |
| 21928830 | 2011 | Retinal degeneration 3 (RD3) protein inhibits catalytic activity of retinal membrane guanylyl cyclase (RetGC) and its stimulation by activating proteins. | 34 |
| 21928830 | 2011 | Retinal degeneration 3 (RD3) protein inhibits catalytic activity of retinal membrane guanylyl cyclase (RetGC) and its stimulation by activating proteins. | 34 |
| 17186464 | 2006 | Premature truncation of a novel protein, RD3, exhibiting subnuclear localization is associated with retinal degeneration. | 72 |
Citation
Dessen P
RD3 (RD3 regulator of GUCY2D)
Atlas Genet Cytogenet Oncol Haematol. 2017-04-01
Online version: http://atlasgeneticsoncology.org/gene/56744/rd3-(rd3-regulator-of-gucy2d)
