Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 55244
MIM: 609832
HGNC: 25588
Ensembl: ENSG00000142494
Variants:
dbSNP: 55244
ClinVar: 55244
TCGA: ENSG00000142494
COSMIC: SLC47A1
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA166163418 | rucaparib | Chemical | LabelAnnotation | associated | |||
| PA443890 | Diabetes Mellitus, Type 2 | Disease | ClinicalAnnotation | associated | PK | PD | 22882994, 23267855, 23873119, 26004431, 28834135 |
| PA445376 | Polycystic Ovary Syndrome | Disease | ClinicalAnnotation | associated | PK | PD | 22882994, 23267855, 23873119, 26004431, 28834135 |
| PA450395 | metformin | Chemical | ClinicalAnnotation, Literature, MultilinkAnnotation, Pathway | associated | PK | PD | 22722338, 22882994, 23267855, 23873119, 24624919, 26004431, 28834135 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36786075 | 2023 | The association study between changes in HbA1C with rs2250486 and rs67238751 genetic variants for SLC47A1 in newly diagnosed Iranian patients with type 2 diabetes mellitus: 6 months follow-up study. | 2 |
| 36786075 | 2023 | The association study between changes in HbA1C with rs2250486 and rs67238751 genetic variants for SLC47A1 in newly diagnosed Iranian patients with type 2 diabetes mellitus: 6 months follow-up study. | 2 |
| 35163393 | 2022 | Transport Turnover Rates for Human OCT2 and MATE1 Expressed in Chinese Hamster Ovary Cells. | 6 |
| 36575162 | 2022 | The lipid flippase SLC47A1 blocks metabolic vulnerability to ferroptosis. | 33 |
| 35163393 | 2022 | Transport Turnover Rates for Human OCT2 and MATE1 Expressed in Chinese Hamster Ovary Cells. | 6 |
| 36575162 | 2022 | The lipid flippase SLC47A1 blocks metabolic vulnerability to ferroptosis. | 33 |
| 32708212 | 2020 | Rapid Regulation of Human Multidrug and Extrusion Transporters hMATE1 and hMATE2K. | 7 |
| 32708212 | 2020 | Rapid Regulation of Human Multidrug and Extrusion Transporters hMATE1 and hMATE2K. | 7 |
| 30910922 | 2019 | Apical Shear Stress Enhanced Organic Cation Transport in Human OCT2/MATE1-Transfected Madin-Darby Canine Kidney Cells Involves Ciliary Sensing. | 9 |
| 30910922 | 2019 | Apical Shear Stress Enhanced Organic Cation Transport in Human OCT2/MATE1-Transfected Madin-Darby Canine Kidney Cells Involves Ciliary Sensing. | 9 |
| 29070695 | 2018 | Relationship between DNA Methylation in the 5' CpG Island of the SLC47A1 (Multidrug and Toxin Extrusion Protein MATE1) Gene and Interindividual Variability in MATE1 Expression in the Human Liver. | 4 |
| 29704007 | 2018 | Contribution of multidrug and toxin extrusion protein 1 (MATE1) to renal secretion of trimethylamine-N-oxide (TMAO). | 10 |
| 30433870 | 2018 | Lack of effect of the SLC47A1 and SLC47A2 gene polymorphisms on the glycemic response to metformin in type 2 diabetes mellitus patients. | 7 |
| 29070695 | 2018 | Relationship between DNA Methylation in the 5' CpG Island of the SLC47A1 (Multidrug and Toxin Extrusion Protein MATE1) Gene and Interindividual Variability in MATE1 Expression in the Human Liver. | 4 |
| 29704007 | 2018 | Contribution of multidrug and toxin extrusion protein 1 (MATE1) to renal secretion of trimethylamine-N-oxide (TMAO). | 10 |
Citation
Dessen P
SLC47A1 (solute carrier family 47 member 1)
Atlas Genet Cytogenet Oncol Haematol. 2017-04-01
Online version: http://atlasgeneticsoncology.org/gene/56745/slc47a1-(solute-carrier-family-47-member-1)
