Identity
HGNC
LOCATION
10q11.23
LOCUSID
ALIAS
ACF,ACF64,ACF65,APOBEC1CF,ASP
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 29974
MIM: 618199
HGNC: 24086
Ensembl: ENSG00000148584
Variants:
dbSNP: 29974
ClinVar: 29974
TCGA: ENSG00000148584
COSMIC: A1CF
RNA/Proteins
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Gene Expression | REACTOME | R-HSA-74160 |
| mRNA Editing | REACTOME | R-HSA-75072 |
| mRNA Editing: C to U Conversion | REACTOME | R-HSA-72200 |
| Formation of the Editosome | REACTOME | R-HSA-75094 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38612387 | 2024 | A1CF Binding to the p65 Interaction Site on NKRF Decreased IFN-β Expression and p65 Phosphorylation (Ser536) in Renal Carcinoma Cells. | 0 |
| 38612387 | 2024 | A1CF Binding to the p65 Interaction Site on NKRF Decreased IFN-β Expression and p65 Phosphorylation (Ser536) in Renal Carcinoma Cells. | 0 |
| 32818382 | 2022 | High APOBEC1 Complementation Factor Expression Positively Modulates the Proliferation, Invasion, and Migration of Endometrial Cancer Cells Through Regulating P53/P21 Signaling Pathway. | 4 |
| 32818382 | 2022 | High APOBEC1 Complementation Factor Expression Positively Modulates the Proliferation, Invasion, and Migration of Endometrial Cancer Cells Through Regulating P53/P21 Signaling Pathway. | 4 |
| 33517564 | 2021 | Both variants of A1CF and BAZ1B genes are associated with gout susceptibility: a replication study and meta-analysis in a Japanese population. | 3 |
| 33517564 | 2021 | Both variants of A1CF and BAZ1B genes are associated with gout susceptibility: a replication study and meta-analysis in a Japanese population. | 3 |
| 30825095 | 2019 | A1CF-Axin2 signal axis regulates apoptosis and migration in Wilms tumor-derived cells through Wnt/β-catenin pathway. | 4 |
| 31186064 | 2019 | Inhibition of the aberrant A1CF-FAM224A-miR-590-3p-ZNF143 positive feedback loop attenuated malignant biological behaviors of glioma cells. | 12 |
| 30825095 | 2019 | A1CF-Axin2 signal axis regulates apoptosis and migration in Wilms tumor-derived cells through Wnt/β-catenin pathway. | 4 |
| 31186064 | 2019 | Inhibition of the aberrant A1CF-FAM224A-miR-590-3p-ZNF143 positive feedback loop attenuated malignant biological behaviors of glioma cells. | 12 |
| 28679452 | 2017 | Interaction of the GCKR and A1CF loci with alcohol consumption to influence the risk of gout. | 15 |
| 28679452 | 2017 | Interaction of the GCKR and A1CF loci with alcohol consumption to influence the risk of gout. | 15 |
| 27231908 | 2016 | EIYMNVPV Motif is Essential for A1CF Nucleus Localization and A1CF (-8aa) Promotes Proliferation of MDA-MB-231 Cells via Up-Regulation of IL-6. | 3 |
| 27231908 | 2016 | EIYMNVPV Motif is Essential for A1CF Nucleus Localization and A1CF (-8aa) Promotes Proliferation of MDA-MB-231 Cells via Up-Regulation of IL-6. | 3 |
| 25902538 | 2015 | Identification of DNA cleavage- and recombination-specific hnRNP cofactors for activation-induced cytidine deaminase. | 14 |
Citation
Dessen P
A1CF (APOBEC1 complementation factor)
Atlas Genet Cytogenet Oncol Haematol. 2017-04-01
Online version: http://atlasgeneticsoncology.org/gene/56761/chromosome-explorer/gene-explorer/
