GMFG (glia maturation factor gamma)

2017-04-01  

Identity

HGNC
LOCATION
19q13.2
LOCUSID
ALIAS
GMF-GAMMA
FUSION GENES

Other Information

Locus ID:

NCBI: 9535
MIM: 604104
HGNC: 4374
Ensembl: ENSG00000130755

Variants:

dbSNP: 9535
ClinVar: 9535
TCGA: ENSG00000130755
COSMIC: GMFG

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000130755ENST00000253054M0R0C1
ENSG00000130755ENST00000594700M0QX47
ENSG00000130755ENST00000595207M0R2P2
ENSG00000130755ENST00000595636M0QXC2
ENSG00000130755ENST00000596583M0QXZ6
ENSG00000130755ENST00000597595O60234
ENSG00000130755ENST00000598034M0QYJ8
ENSG00000130755ENST00000600322M0R0C1
ENSG00000130755ENST00000601387M0R1D2
ENSG00000130755ENST00000602185M0QYG8

Expression (GTEx)

0
50
100
150
200
250
300

Pathways

PathwaySourceExternal ID
Immune SystemREACTOMER-HSA-168256
Innate Immune SystemREACTOMER-HSA-168249
Neutrophil degranulationREACTOMER-HSA-6798695

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
373723372023High Level of GMFG Correlated to Poor Clinical Outcome and Promoted Cell Migration and Invasion through EMT Pathway in Triple-Negative Breast Cancer.0
373723372023High Level of GMFG Correlated to Poor Clinical Outcome and Promoted Cell Migration and Invasion through EMT Pathway in Triple-Negative Breast Cancer.0
351038562022RNF144A exerts tumor suppressor function in breast cancer through targeting YY1 for proteasomal degradation to downregulate GMFG expression.5
353835312022GMFG (glia maturation factor gamma) inhibits lung cancer growth by activating p53 signaling pathway.6
351038562022RNF144A exerts tumor suppressor function in breast cancer through targeting YY1 for proteasomal degradation to downregulate GMFG expression.5
353835312022GMFG (glia maturation factor gamma) inhibits lung cancer growth by activating p53 signaling pathway.6
338632932021Bioinformatics and survival analysis of glia maturation factor-γ in pan-cancers.9
338632932021Bioinformatics and survival analysis of glia maturation factor-γ in pan-cancers.9
308119452019Phosphorylation of GMFγ by c-Abl Coordinates Lamellipodial and Focal Adhesion Dynamics to Regulate Airway Smooth Muscle Cell Migration.13
308119452019Phosphorylation of GMFγ by c-Abl Coordinates Lamellipodial and Focal Adhesion Dynamics to Regulate Airway Smooth Muscle Cell Migration.13
280754542017Expression of glia maturation factor γ is associated with colorectal cancer metastasis and its downregulation suppresses colorectal cancer cell migration and invasion in vitro.14
280754542017Expression of glia maturation factor γ is associated with colorectal cancer metastasis and its downregulation suppresses colorectal cancer cell migration and invasion in vitro.14
268959642016Glia Maturation Factor-γ Regulates Monocyte Migration through Modulation of β1-Integrin.21
268959642016Glia Maturation Factor-γ Regulates Monocyte Migration through Modulation of β1-Integrin.21
248185512014Glia maturation factor-γ phosphorylation at Tyr-104 regulates actin dynamics and contraction in human airway smooth muscle.29

Citation

Dessen P

GMFG (glia maturation factor gamma)

Atlas Genet Cytogenet Oncol Haematol. 2017-04-01

Online version: http://atlasgeneticsoncology.org/gene/56763/gmfg-(glia-maturation-factor-gamma)