HDGFL3 (HDGF like 3)

2017-04-01  

Identity

HGNC
LOCATION
15q25.2
LOCUSID
ALIAS
CGI-142,HDGF-2,HDGF2,HDGFRP3,HRP-3

Other Information

Locus ID:

NCBI: 50810
MIM: 616643
HGNC: 24937
Ensembl: ENSG00000166503

Variants:

dbSNP: 50810
ClinVar: 50810
TCGA: ENSG00000166503
COSMIC: HDGFL3

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000166503ENST00000299633Q9Y3E1
ENSG00000166503ENST00000299633A0A024R216
ENSG00000166503ENST00000563404H3BPQ6
ENSG00000166503ENST00000563790H3BPQ6
ENSG00000166503ENST00000568294H3BPM9

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
367948492023HDGFRP3 interaction with 53BP1 promotes DNA double-strand break repair.5
376813342023Bulk RNA-Seq Combined with Single-Cell Transcriptome Sequencing Reveals the Possible Mechanisms by Which HDGFL3 Involves in Prostate Cancer Growth and Metastasis.0
367948492023HDGFRP3 interaction with 53BP1 promotes DNA double-strand break repair.5
376813342023Bulk RNA-Seq Combined with Single-Cell Transcriptome Sequencing Reveals the Possible Mechanisms by Which HDGFL3 Involves in Prostate Cancer Growth and Metastasis.0
347146042022A novel function of HRP-3 in regulating cell cycle progression via the HDAC-E2F1-Cyclin E pathway in lung cancer.4
347146042022A novel function of HRP-3 in regulating cell cycle progression via the HDAC-E2F1-Cyclin E pathway in lung cancer.4
288548472019RNA sequencing of bipolar disorder lymphoblastoid cell lines implicates the neurotrophic factor HRP-3 in lithium's clinical efficacy.6
311626072019The HRP3 PWWP domain recognizes the minor groove of double-stranded DNA and recruits HRP3 to chromatin.10
288548472019RNA sequencing of bipolar disorder lymphoblastoid cell lines implicates the neurotrophic factor HRP-3 in lithium's clinical efficacy.6
311626072019The HRP3 PWWP domain recognizes the minor groove of double-stranded DNA and recruits HRP3 to chromatin.10
268237542015HRP-3 protects the hepatoma cells from glucose deprivation-induced apoptosis.4
268237542015HRP-3 protects the hepatoma cells from glucose deprivation-induced apoptosis.4
240126732013Depletion of hepatoma-derived growth factor-related protein-3 induces apoptotic sensitization of radioresistant A549 cells via reactive oxygen species-dependent p53 activation.5
240126732013Depletion of hepatoma-derived growth factor-related protein-3 induces apoptotic sensitization of radioresistant A549 cells via reactive oxygen species-dependent p53 activation.5
192375402009Hepatoma-derived growth factor-related protein-3 interacts with microtubules and promotes neurite outgrowth in mouse cortical neurons.10

Citation

Dessen P

HDGFL3 (HDGF like 3)

Atlas Genet Cytogenet Oncol Haematol. 2017-04-01

Online version: http://atlasgeneticsoncology.org/gene/56766/hdgfl3-(hdgf-like-3)