TRIM14 (tripartite motif containing 14)

2017-04-01  

Identity

HGNC
TRIM14
LOCATION
9q22.33
LOCUSID
9830
ALIAS
-
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 9830
MIM: 606556
HGNC: 16283
Ensembl: ENSG00000106785

Variants:

dbSNP: 9830
ClinVar: 9830
TCGA: ENSG00000106785
COSMIC: TRIM14

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000106785ENST00000341469Q14142
ENSG00000106785ENST00000341469A0A024R165
ENSG00000106785ENST00000342043Q14142
ENSG00000106785ENST00000342043A0A024R165
ENSG00000106785ENST00000375098Q14142
ENSG00000106785ENST00000375098A0A024R165
ENSG00000106785ENST00000475147F2Z2M2

Expression (GTEx)

0
5
10
15
20
25
30
35
40
45
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Immune SystemREACTOMER-HSA-168256
Cytokine Signaling in Immune systemREACTOMER-HSA-1280215
Interferon SignalingREACTOMER-HSA-913531
Interferon gamma signalingREACTOMER-HSA-877300

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
382678122024TRIM14 suppressed the progression of NSCLC via hexosamine biosynthesis pathway.0
386974632024Trim14-IκBα Signaling Regulates Chronic Inflammatory Pain in Rats and Osteoarthritis Patients.0
382678122024TRIM14 suppressed the progression of NSCLC via hexosamine biosynthesis pathway.0
386974632024Trim14-IκBα Signaling Regulates Chronic Inflammatory Pain in Rats and Osteoarthritis Patients.0
376287772023TRIM14 Overexpression Induces Chemoresistance and Malignant Behaviors of Hepatocellular Carcinoma Cells by Activating the STAT3/HIF-1α Pathway.0
376287772023TRIM14 Overexpression Induces Chemoresistance and Malignant Behaviors of Hepatocellular Carcinoma Cells by Activating the STAT3/HIF-1α Pathway.0
347870662022Circular RNA circ_0048764 promotes the development of breast cancer by regulating microRNA-1296-5p/tripartite motif containing 14 axis.7
347870662022Circular RNA circ_0048764 promotes the development of breast cancer by regulating microRNA-1296-5p/tripartite motif containing 14 axis.7
338640332021Human TRIM14 protects transgenic mice from influenza A viral infection without activation of other innate immunity pathways.2
339826662021TRIM14 regulates melanoma malignancy via PTEN/PI3K/AKT and STAT3 pathways.8
340510072021miR-4443 targets TRIM14 to suppress metastasis and energy metabolism of papillary thyroid carcinoma (PTC) in vitro.9
342926522021miR-671-5p repressed progression of papillary thyroid carcinoma via TRIM14.6
346560782021Human mesenchymal stem cells derived exosomes inhibit the growth of acute myeloid leukemia cells via regulating miR-23b-5p/TRIM14 pathway.12
338640332021Human TRIM14 protects transgenic mice from influenza A viral infection without activation of other innate immunity pathways.2
339826662021TRIM14 regulates melanoma malignancy via PTEN/PI3K/AKT and STAT3 pathways.8

Citation

Dessen P

TRIM14 (tripartite motif containing 14)

Atlas Genet Cytogenet Oncol Haematol. 2017-04-01

Online version: http://atlasgeneticsoncology.org/gene/56768/trim14-(tripartite-motif-containing-14)