CAVIN1 (caveolae associated protein 1)

2017-04-01  

Identity

HGNC
CAVIN1
LOCATION
17q21.2
LOCUSID
284119
ALIAS
CAVIN,CGL4,FKSG13,PTRF,cavin-1

Other Information

Locus ID:

NCBI: 284119
MIM: 603198
HGNC: 9688
Ensembl: ENSG00000177469

Variants:

dbSNP: 284119
ClinVar: 284119
TCGA: ENSG00000177469
COSMIC: CAVIN1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000177469ENST00000357037Q6NZI2

Pathways

PathwaySourceExternal ID
Gene ExpressionREACTOMER-HSA-74160
RNA Polymerase I, RNA Polymerase III, and Mitochondrial TranscriptionREACTOMER-HSA-504046
RNA Polymerase I TranscriptionREACTOMER-HSA-73864
RNA Polymerase I Transcription TerminationREACTOMER-HSA-73863

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
377748372024Cavin1 activates the Wnt/β-catenin pathway to influence the proliferation and migration of hepatocellular carcinoma.0
380921442024Neovascularization directed by CAVIN1/CCBE1/VEGFC confers TMZ-resistance in glioblastoma.0
377748372024Cavin1 activates the Wnt/β-catenin pathway to influence the proliferation and migration of hepatocellular carcinoma.0
380921442024Neovascularization directed by CAVIN1/CCBE1/VEGFC confers TMZ-resistance in glioblastoma.0
373224082023Molecular and clinical characterization of PTRF in glioma via 1,022 samples.0
373224082023Molecular and clinical characterization of PTRF in glioma via 1,022 samples.0
334967262021Caveolin-1 and cavin1 act synergistically to generate a unique lipid environment in caveolae.20
350695872021PTRF/Cavin-1 as a Novel RNA-Binding Protein Expedites the NF-κB/PD-L1 Axis by Stabilizing lncRNA NEAT1, Contributing to Tumorigenesis and Immune Evasion in Glioblastoma.16
334967262021Caveolin-1 and cavin1 act synergistically to generate a unique lipid environment in caveolae.20
350695872021PTRF/Cavin-1 as a Novel RNA-Binding Protein Expedites the NF-κB/PD-L1 Axis by Stabilizing lncRNA NEAT1, Contributing to Tumorigenesis and Immune Evasion in Glioblastoma.16
314486732020CAV1-CAVIN1-LC3B-mediated autophagy regulates high glucose-stimulated LDL transcytosis.30
316056052020PTRF/CAVIN1, regulated by SHC1 through the EGFR pathway, is found in urine exosomes as a potential biomarker of ccRCC.22
317065702020Interaction of cavin-1/PTRF leucine zipper domain 2 and its congenital generalized lipodystrophy mutant with model membranes.0
320654712020A role for caveola-forming proteins caveolin-1 and CAVIN1 in the pro-invasive response of glioblastoma to osmotic and hydrostatic pressure.6
324936992020Stromal CAVIN1 Controls Prostate Cancer Microenvironment and Metastasis by Modulating Lipid Distribution and Inflammatory Signaling.9

Citation

Dessen P

CAVIN1 (caveolae associated protein 1)

Atlas Genet Cytogenet Oncol Haematol. 2017-04-01

Online version: http://atlasgeneticsoncology.org/gene/56788/cavin1-(caveolae-associated-protein-1)