CAVIN1 (caveolae associated protein 1)

2017-04-01  

Identity

HGNC
LOCATION
17q21.2
LOCUSID
ALIAS
CAVIN,CGL4,FKSG13,PTRF,cavin-1

Other Information

Locus ID:

NCBI: 284119
MIM: 603198
HGNC: 9688
Ensembl: ENSG00000177469

Variants:

dbSNP: 284119
ClinVar: 284119
TCGA: ENSG00000177469
COSMIC: CAVIN1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000177469ENST00000357037Q6NZI2

Pathways

PathwaySourceExternal ID
Gene ExpressionREACTOMER-HSA-74160
RNA Polymerase I, RNA Polymerase III, and Mitochondrial TranscriptionREACTOMER-HSA-504046
RNA Polymerase I TranscriptionREACTOMER-HSA-73864
RNA Polymerase I Transcription TerminationREACTOMER-HSA-73863

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
190682162009Investigation of Crohn's disease risk loci in ulcerative colitis further defines their molecular relationship.53
244730722013Single-molecule analysis reveals self assembly and nanoscale segregation of two distinct cavin subcomplexes on caveolae.39
207327282011PTRF-cavin-1 expression decreases the migration of PC3 prostate cancer cells: role of matrix metalloprotease 9.23
224618952012PTRF/cavin-1 and MIF proteins are identified as non-small cell lung cancer biomarkers by label-free proteomics.23
170269592006Association and insulin regulated translocation of hormone-sensitive lipase with PTRF.22
219132172012Down-regulation of the cavin family proteins in breast cancer.21
278347312016Model for the architecture of caveolae based on a flexible, net-like assembly of Cavin1 and Caveolin discs.21
211524012010IGF-IR internalizes with Caveolin-1 and PTRF/Cavin in HaCat cells.19
237708572014Cavin-1 is essential for the tumor-promoting effect of caveolin-1 and enhances its prognostic potency in pancreatic cancer.18
239341892014PTRF/cavin-1 neutralizes non-caveolar caveolin-1 microdomains in prostate cancer.18

Citation

Dessen P

CAVIN1 (caveolae associated protein 1)

Atlas Genet Cytogenet Oncol Haematol. 2017-04-01

Online version: http://atlasgeneticsoncology.org/gene/56788/cavin1-(caveolae-associated-protein-1)