Identity
HGNC
LOCATION
12q13.3
LOCUSID
ALIAS
COXFA4L2,MISTRH,NUOMS
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 56901
HGNC: 29836
Ensembl: ENSG00000185633
Variants:
dbSNP: 56901
ClinVar: 56901
TCGA: ENSG00000185633
COSMIC: NDUFA4L2
RNA/Proteins
Expression (GTEx)
Pathways
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 35929074 | 2023 | Unique expression of the atypical mitochondrial subunit NDUFA4L2 in cerebral pericytes fine tunes HIF activity in response to hypoxia. | 2 |
| 36369883 | 2023 | Transcriptional regulation of NDUFA4L2 by NFIB induces sorafenib resistance by decreasing reactive oxygen species in hepatocellular carcinoma. | 6 |
| 36722045 | 2023 | NDUFA4L2 reduces mitochondrial respiration resulting in defective lysosomal trafficking in clear cell renal cell carcinoma. | 4 |
| 35929074 | 2023 | Unique expression of the atypical mitochondrial subunit NDUFA4L2 in cerebral pericytes fine tunes HIF activity in response to hypoxia. | 2 |
| 36369883 | 2023 | Transcriptional regulation of NDUFA4L2 by NFIB induces sorafenib resistance by decreasing reactive oxygen species in hepatocellular carcinoma. | 6 |
| 36722045 | 2023 | NDUFA4L2 reduces mitochondrial respiration resulting in defective lysosomal trafficking in clear cell renal cell carcinoma. | 4 |
| 33340241 | 2021 | NDUFA4L2 in smooth muscle promotes vascular remodeling in hypoxic pulmonary arterial hypertension. | 11 |
| 33828084 | 2021 | NDUFA4L2 promotes glioblastoma progression, is associated with poor survival, and can be effectively targeted by apatinib. | 13 |
| 33340241 | 2021 | NDUFA4L2 in smooth muscle promotes vascular remodeling in hypoxic pulmonary arterial hypertension. | 11 |
| 33828084 | 2021 | NDUFA4L2 promotes glioblastoma progression, is associated with poor survival, and can be effectively targeted by apatinib. | 13 |
| 33066813 | 2020 | Evaluating the clinical significance of SHMT2 and its co-expressed gene in human kidney cancer. | 8 |
| 33066813 | 2020 | Evaluating the clinical significance of SHMT2 and its co-expressed gene in human kidney cancer. | 8 |
| 30710412 | 2019 | Mitochondrial NDUFA4L2 protein promotes the vitality of lung cancer cells by repressing oxidative stress. | 19 |
| 30710412 | 2019 | Mitochondrial NDUFA4L2 protein promotes the vitality of lung cancer cells by repressing oxidative stress. | 19 |
| 29953852 | 2018 | Induction of the mitochondrial NDUFA4L2 protein by HIF-1a regulates heart regeneration by promoting the survival of cardiac stem cell. | 11 |
Citation
Dessen P
NDUFA4L2 (NDUFA4 mitochondrial complex associated like 2)
Atlas Genet Cytogenet Oncol Haematol. 2017-04-01
Online version: http://atlasgeneticsoncology.org/gene/56790/ndufa4l2-(ndufa4-mitochondrial-complex-associated-like-2)
