DLGAP2 (DLG associated protein 2)

2017-04-01  

Identity

HGNC
DLGAP2
LOCATION
8p23.3
LOCUSID
9228
ALIAS
C8orf68,DAP2,ERICH1-AS1,SAPAP2
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 9228
MIM: 605438
HGNC: 2906
Ensembl: ENSG00000198010

Variants:

dbSNP: 9228
ClinVar: 9228
TCGA: ENSG00000198010
COSMIC: DLGAP2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000198010ENST00000421627Q9P1A6
ENSG00000198010ENST00000518530A0A0J9YWL8
ENSG00000198010ENST00000520901H0YBY6
ENSG00000198010ENST00000522499A0A0J9YY16
ENSG00000198010ENST00000612087A0A1B0GXK6
ENSG00000198010ENST00000637795A0A1B0GTN4

Expression (GTEx)

0
1
2
3
4
5
6
7
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Neuronal SystemREACTOMER-HSA-112316
Protein-protein interactions at synapsesREACTOMER-HSA-6794362
Interactions of neurexins and neuroligins at synapsesREACTOMER-HSA-6794361

Protein levels (Protein atlas)

Not detected
Low
Medium
High
N/A

References

Pubmed IDYearTitleCitations
387657312023DNA Methylation Near DLGAP2 May Mediate the Relationship between Family History of Type 1 Diabetes and Type 1 Diabetes Risk.0
387657312023DNA Methylation Near DLGAP2 May Mediate the Relationship between Family History of Type 1 Diabetes and Type 1 Diabetes Risk.0
314510812020Cannabis use is associated with potentially heritable widespread changes in autism candidate gene DLGAP2 DNA methylation in sperm.50
328776732020Cross-Species Analyses Identify Dlgap2 as a Regulator of Age-Related Cognitive Decline and Alzheimer's Dementia.16
314510812020Cannabis use is associated with potentially heritable widespread changes in autism candidate gene DLGAP2 DNA methylation in sperm.50
328776732020Cross-Species Analyses Identify Dlgap2 as a Regulator of Age-Related Cognitive Decline and Alzheimer's Dementia.16
305047792018Quantitative DNA Methylation Analysis of DLGAP2 Gene using Pyrosequencing in Schizophrenia with Tardive Dyskinesia: A Linear Mixed Model Approach.8
305047792018Quantitative DNA Methylation Analysis of DLGAP2 Gene using Pyrosequencing in Schizophrenia with Tardive Dyskinesia: A Linear Mixed Model Approach.8
253913832015Genetic variation in imprinted genes is associated with risk of late-onset Alzheimer's disease.16
263939132015Three circulating long non-coding RNAs act as biomarkers for predicting NSCLC.28
253913832015Genetic variation in imprinted genes is associated with risk of late-onset Alzheimer's disease.16
263939132015Three circulating long non-coding RNAs act as biomarkers for predicting NSCLC.28
244163982014Role of the DLGAP2 gene encoding the SAP90/PSD-95-associated protein 2 in schizophrenia.26
244163982014Role of the DLGAP2 gene encoding the SAP90/PSD-95-associated protein 2 in schizophrenia.26
231540992013Glutamate system genes and brain volume alterations in pediatric obsessive-compulsive disorder: a preliminary study.27

Citation

Dessen P

DLGAP2 (DLG associated protein 2)

Atlas Genet Cytogenet Oncol Haematol. 2017-04-01

Online version: http://atlasgeneticsoncology.org/gene/56805/dlgap2-(dlg-associated-protein-2)