FANK1 (fibronectin type III and ankyrin repeat domains 1)

2017-04-01  

Identity

HGNC
FANK1
LOCATION
10q26.2
LOCUSID
92565
ALIAS
HSD13
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 92565
MIM: 611640
HGNC: 23527
Ensembl: ENSG00000203780

Variants:

dbSNP: 92565
ClinVar: 92565
TCGA: ENSG00000203780
COSMIC: FANK1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000203780ENST00000368689A6NKD7
ENSG00000203780ENST00000368691A6NP17
ENSG00000203780ENST00000368693Q8TC84
ENSG00000203780ENST00000417114C9JD80
ENSG00000203780ENST00000445510A0A1B0GX87
ENSG00000203780ENST00000456942H7C3M3

Expression (GTEx)

0
10
20
30
40
50
60
70
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

References

Pubmed IDYearTitleCitations
192400612009Coeliac disease-associated risk variants in TNFAIP3 and REL implicate altered NF-kappaB signalling.75
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.62
251447062014A model-based approach for identifying signatures of ancient balancing selection in genetic data.56
209788192011Fank1 interacts with Jab1 and regulates cell apoptosis via the AP-1 pathway.15
186827982008Genes to diseases (G2D) computational method to identify asthma candidate genes.10
176042332007Fank1 is a testis-specific gene encoding a nuclear protein exclusively expressed during the transition from the meiotic to the haploid phase of spermatogenesis.9
270604962016Proapoptotic RYBP interacts with FANK1 and induces tumor cell apoptosis through the AP-1 signaling pathway.7
255155832014Targeting the fibronectin type III repeats in tenascin-C inhibits epithelial-mesenchymal transition in the context of posterior capsular opacification.6

Citation

Dessen P

FANK1 (fibronectin type III and ankyrin repeat domains 1)

Atlas Genet Cytogenet Oncol Haematol. 2017-04-01

Online version: http://atlasgeneticsoncology.org/gene/56807/fank1-(fibronectin-type-iii-and-ankyrin-repeat-domains-1)