Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 3234
MIM: 142985
HGNC: 5139
Ensembl: ENSG00000175879
Variants:
dbSNP: 3234
ClinVar: 3234
TCGA: ENSG00000175879
COSMIC: HOXD8
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000175879 | ENST00000313173 | P13378 |
| ENSG00000175879 | ENST00000429017 | A0A0A0MSX5 |
| ENSG00000175879 | ENST00000450510 | P13378 |
| ENSG00000175879 | ENST00000544999 | A0A0A0MTF4 |
Expression (GTEx)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 35177798 | 2022 | HOXD8 hypermethylation as a fully sensitive and specific biomarker for biliary tract cancer detectable in tissue and bile samples. | 9 |
| 35426617 | 2022 | CircTMEM59 Serves as miR-410-3p Sponge to Inhibit the Proliferation and Metastasis of Colorectal Cancer by Regulating HOXD8. | 4 |
| 35177798 | 2022 | HOXD8 hypermethylation as a fully sensitive and specific biomarker for biliary tract cancer detectable in tissue and bile samples. | 9 |
| 35426617 | 2022 | CircTMEM59 Serves as miR-410-3p Sponge to Inhibit the Proliferation and Metastasis of Colorectal Cancer by Regulating HOXD8. | 4 |
| 34454307 | 2021 | HOXD8 inhibits the proliferation and migration of triple-negative breast cancer cells and induces apoptosis in them through regulation of AKT/mTOR pathway. | 8 |
| 34454307 | 2021 | HOXD8 inhibits the proliferation and migration of triple-negative breast cancer cells and induces apoptosis in them through regulation of AKT/mTOR pathway. | 8 |
| 33311496 | 2020 | LINC01106 post-transcriptionally regulates ELK3 and HOXD8 to promote bladder cancer progression. | 16 |
| 33311496 | 2020 | LINC01106 post-transcriptionally regulates ELK3 and HOXD8 to promote bladder cancer progression. | 16 |
| 30626726 | 2019 | HOXD8/DIAPH2-AS1 epigenetically regulates PAX3 and impairs HTR-8/SVneo cell function under hypoxia. | 4 |
| 30941968 | 2019 | MiR-5692a promotes proliferation and inhibits apoptosis by targeting HOXD8 in hepatocellular carcinoma. | 10 |
| 30626726 | 2019 | HOXD8/DIAPH2-AS1 epigenetically regulates PAX3 and impairs HTR-8/SVneo cell function under hypoxia. | 4 |
| 30941968 | 2019 | MiR-5692a promotes proliferation and inhibits apoptosis by targeting HOXD8 in hepatocellular carcinoma. | 10 |
| 30194340 | 2018 | Potential role of the HOXD8 transcription factor in cisplatin resistance and tumour metastasis in advanced epithelial ovarian cancer. | 12 |
| 30194340 | 2018 | Potential role of the HOXD8 transcription factor in cisplatin resistance and tumour metastasis in advanced epithelial ovarian cancer. | 12 |
| 28457970 | 2017 | HOXD8 exerts a tumor-suppressing role in colorectal cancer as an apoptotic inducer. | 24 |
Citation
Dessen P
HOXD8 (homeobox D8)
Atlas Genet Cytogenet Oncol Haematol. 2017-04-01
Online version: http://atlasgeneticsoncology.org/gene/56821/hoxd8-(homeobox-d8)
