Identity
HGNC
LOCATION
7q22.1
LOCUSID
ALIAS
CENP-33,ORCA
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 222229
MIM: 615167
HGNC: 21769
Ensembl: ENSG00000161036
Variants:
dbSNP: 222229
ClinVar: 222229
TCGA: ENSG00000161036
COSMIC: LRWD1
RNA/Proteins
Expression (GTEx)
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38385979 | 2024 | MicroRNA-320a enhances LRWD1 expression through the AGO2/FXR1-dependent pathway to affect cell behaviors and the oxidative stress response in human testicular embryonic carcinoma cells. | 0 |
| 38385979 | 2024 | MicroRNA-320a enhances LRWD1 expression through the AGO2/FXR1-dependent pathway to affect cell behaviors and the oxidative stress response in human testicular embryonic carcinoma cells. | 0 |
| 28569402 | 2018 | LRWD1 Regulates Microtubule Nucleation and Proper Cell Cycle Progression in the Human Testicular Embryonic Carcinoma Cells. | 7 |
| 29544732 | 2018 | Nuclear factor erythroid-2-related factor regulates LRWD1 expression and cellular adaptation to oxidative stress in human embryonal carcinoma cells. | 2 |
| 28569402 | 2018 | LRWD1 Regulates Microtubule Nucleation and Proper Cell Cycle Progression in the Human Testicular Embryonic Carcinoma Cells. | 7 |
| 29544732 | 2018 | Nuclear factor erythroid-2-related factor regulates LRWD1 expression and cellular adaptation to oxidative stress in human embryonal carcinoma cells. | 2 |
| 27760381 | 2017 | High-throughput RNAi screen in Ewing sarcoma cells identifies leucine rich repeats and WD repeat domain containing 1 (LRWD1) as a regulator of EWS-FLI1 driven cell viability. | 10 |
| 27760381 | 2017 | High-throughput RNAi screen in Ewing sarcoma cells identifies leucine rich repeats and WD repeat domain containing 1 (LRWD1) as a regulator of EWS-FLI1 driven cell viability. | 10 |
| 25922909 | 2015 | The preRC protein ORCA organizes heterochromatin by assembling histone H3 lysine 9 methyltransferases on chromatin. | 30 |
| 25922909 | 2015 | The preRC protein ORCA organizes heterochromatin by assembling histone H3 lysine 9 methyltransferases on chromatin. | 30 |
| 23445371 | 2014 | Single-nucleotide polymorphisms in the LRWD1 gene may be a genetic risk factor for Japanese patients with Sertoli cell-only syndrome. | 5 |
| 25170821 | 2014 | Correlation between leucine rich domain and the stability of LRWD1 protein in human NT2/D1 cells. | 0 |
| 23445371 | 2014 | Single-nucleotide polymorphisms in the LRWD1 gene may be a genetic risk factor for Japanese patients with Sertoli cell-only syndrome. | 5 |
| 25170821 | 2014 | Correlation between leucine rich domain and the stability of LRWD1 protein in human NT2/D1 cells. | 0 |
| 22427655 | 2012 | Leucine-rich repeat and WD repeat-containing protein 1 is recruited to pericentric heterochromatin by trimethylated lysine 9 of histone H3 and maintains heterochromatin silencing. | 24 |
Citation
Dessen P
LRWD1 (leucine rich repeats and WD repeat domain containing 1)
Atlas Genet Cytogenet Oncol Haematol. 2017-04-01
Online version: http://atlasgeneticsoncology.org/gene/56845/lrwd1-(leucine-rich-repeats-and-wd-repeat-domain-containing-1)
