Identity
HGNC
LOCATION
2p13.3
LOCUSID
ALIAS
CMS12,CMSTA1,GFA,GFAT,GFAT
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 2673
MIM: 138292
HGNC: 4241
Ensembl: ENSG00000198380
Variants:
dbSNP: 2673
ClinVar: 2673
TCGA: ENSG00000198380
COSMIC: GFPT1
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000198380 | ENST00000357308 | Q06210 |
| ENSG00000198380 | ENST00000361060 | Q06210 |
Expression (GTEx)
Pathways
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38732103 | 2024 | Overexpression of Fatty Acid Synthase Upregulates Glutamine-Fructose-6-Phosphate Transaminase 1 and O-Linked N-Acetylglucosamine Transferase to Increase O-GlcNAc Protein Glycosylation and Promote Colorectal Cancer Growth. | 0 |
| 38732103 | 2024 | Overexpression of Fatty Acid Synthase Upregulates Glutamine-Fructose-6-Phosphate Transaminase 1 and O-Linked N-Acetylglucosamine Transferase to Increase O-GlcNAc Protein Glycosylation and Promote Colorectal Cancer Growth. | 0 |
| 34978387 | 2022 | Diverse myopathological features in the congenital myasthenia syndrome with GFPT1 mutation. | 4 |
| 35694932 | 2022 | GFPT1-Associated Congenital Myasthenic Syndrome Mimicking a Glycogen Storage Disease - Diagnostic Pitfalls in Myopathology Solved by Next-Generation-Sequencing. | 1 |
| 36040914 | 2022 | GFPT1 promotes the proliferation of cervical cancer via regulating the ubiquitination and degradation of PTEN. | 5 |
| 34978387 | 2022 | Diverse myopathological features in the congenital myasthenia syndrome with GFPT1 mutation. | 4 |
| 35694932 | 2022 | GFPT1-Associated Congenital Myasthenic Syndrome Mimicking a Glycogen Storage Disease - Diagnostic Pitfalls in Myopathology Solved by Next-Generation-Sequencing. | 1 |
| 36040914 | 2022 | GFPT1 promotes the proliferation of cervical cancer via regulating the ubiquitination and degradation of PTEN. | 5 |
| 33517899 | 2021 | High GFPT1 expression predicts unfavorable outcomes in patients with resectable pancreatic ductal adenocarcinoma. | 5 |
| 34270713 | 2021 | Inhibition of GFAT1 in lung cancer cells destabilizes PD-L1 protein. | 8 |
| 34735873 | 2021 | Cardiomyocyte protein O-GlcNAcylation is regulated by GFAT1 not GFAT2. | 9 |
| 33517899 | 2021 | High GFPT1 expression predicts unfavorable outcomes in patients with resectable pancreatic ductal adenocarcinoma. | 5 |
| 34270713 | 2021 | Inhibition of GFAT1 in lung cancer cells destabilizes PD-L1 protein. | 8 |
| 34735873 | 2021 | Cardiomyocyte protein O-GlcNAcylation is regulated by GFAT1 not GFAT2. | 9 |
| 32019926 | 2020 | Loss of GFAT-1 feedback regulation activates the hexosamine pathway that modulates protein homeostasis. | 23 |
Citation
Dessen P
GFPT1 (glutamine--fructose-6-phosphate transaminase 1)
Atlas Genet Cytogenet Oncol Haematol. 2017-04-01
Online version: http://atlasgeneticsoncology.org/gene/56861/gfpt1-(glutamine-fructose-6-phosphate-transaminase-1)
