HDGFL2 (HDGF like 2)

2017-04-01  

Identity

HGNC
LOCATION
19p13.3
LOCUSID
ALIAS
HDGF-2,HDGF2,HDGFRP2,HRP-2,HRP2

Other Information

Locus ID:

NCBI: 84717
MIM: 617884
HGNC: 14680
Ensembl: ENSG00000167674

Variants:

dbSNP: 84717
ClinVar: 84717
TCGA: ENSG00000167674
COSMIC: HDGFL2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000167674ENST00000587016K7ERA4
ENSG00000167674ENST00000589486K7EJP7
ENSG00000167674ENST00000592417K7EPS6
ENSG00000167674ENST00000592691K7EQ06
ENSG00000167674ENST00000601353M0R0J3
ENSG00000167674ENST00000614903A0A087WZ99
ENSG00000167674ENST00000615225A0A087WT54
ENSG00000167674ENST00000616600Q7Z4V5
ENSG00000167674ENST00000619255A0A087WX58
ENSG00000167674ENST00000621835Q7Z4V5

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
351662402022Epigenomic reprogramming via HRP2-MINA dictates response to proteasome inhibitors in multiple myeloma with t(4;14) translocation.10
351662402022Epigenomic reprogramming via HRP2-MINA dictates response to proteasome inhibitors in multiple myeloma with t(4;14) translocation.10
334779702021Unlike Its Paralog LEDGF/p75, HRP-2 Is Dispensable for MLL-R Leukemogenesis but Important for Leukemic Cell Survival.4
334779702021Unlike Its Paralog LEDGF/p75, HRP-2 Is Dispensable for MLL-R Leukemogenesis but Important for Leukemic Cell Survival.4
316167952019LEDGF and HDGF2 relieve the nucleosome-induced barrier to transcription in differentiated cells.48
316167952019LEDGF and HDGF2 relieve the nucleosome-induced barrier to transcription in differentiated cells.48
267213872016Hepatoma-derived growth factor-related protein 2 promotes DNA repair by homologous recombination.25
267213872016Hepatoma-derived growth factor-related protein 2 promotes DNA repair by homologous recombination.25
256897192015HDGF-related protein-2 (HRP-2) acts as an oncogene to promote cell growth in hepatocellular carcinoma.5
256897192015HDGF-related protein-2 (HRP-2) acts as an oncogene to promote cell growth in hepatocellular carcinoma.5
230466032012HRP-2 determines HIV-1 integration site selection in LEDGF/p75 depleted cells.43
230466032012HRP-2 determines HIV-1 integration site selection in LEDGF/p75 depleted cells.43
163379832006Biochemical and genetic analyses of integrase-interacting proteins lens epithelium-derived growth factor (LEDGF)/p75 and hepatoma-derived growth factor related protein 2 (HRP2) in preintegration complex function and HIV-1 replication.63
163379832006Biochemical and genetic analyses of integrase-interacting proteins lens epithelium-derived growth factor (LEDGF)/p75 and hepatoma-derived growth factor related protein 2 (HRP2) in preintegration complex function and HIV-1 replication.63

Citation

Dessen P

HDGFL2 (HDGF like 2)

Atlas Genet Cytogenet Oncol Haematol. 2017-04-01

Online version: http://atlasgeneticsoncology.org/gene/56870/hdgfl2-(hdgf-like-2)