Identity
HGNC
LOCATION
9q34.3
LOCUSID
ALIAS
BIII,CACNL1A5,CACNN,Cav2.2,DYT23,NEDNEH
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 774
MIM: 601012
HGNC: 1389
Ensembl: ENSG00000148408
Variants:
dbSNP: 774
ClinVar: 774
TCGA: ENSG00000148408
COSMIC: CACNA1B
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA33748 | PRKACA | Gene | Pathway | associated | |||
| PA33749 | PRKACB | Gene | Pathway | associated | |||
| PA33750 | PRKACG | Gene | Pathway | associated | |||
| PA448871 | celecoxib | Chemical | Pathway | associated | 22336956 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38157867 | 2024 | An orally available Ca(v)2.2 calcium channel inhibitor for the treatment of neuropathic pain. | 0 |
| 38157867 | 2024 | An orally available Ca(v)2.2 calcium channel inhibitor for the treatment of neuropathic pain. | 0 |
| 33100116 | 2022 | CACNA1B facilitates breast cancer cell growth and migration by regulating cyclin D1 and EMT: the implication of CACNA1B in breast cancer. | 1 |
| 35777045 | 2022 | High expression of N-type calcium channel indicates a favorable prognosis in gliomas. | 1 |
| 36137995 | 2022 | Ca(v)2.2-NFAT2-USP43 axis promotes invadopodia formation and breast cancer metastasis through cortactin stabilization. | 8 |
| 33100116 | 2022 | CACNA1B facilitates breast cancer cell growth and migration by regulating cyclin D1 and EMT: the implication of CACNA1B in breast cancer. | 1 |
| 35777045 | 2022 | High expression of N-type calcium channel indicates a favorable prognosis in gliomas. | 1 |
| 36137995 | 2022 | Ca(v)2.2-NFAT2-USP43 axis promotes invadopodia formation and breast cancer metastasis through cortactin stabilization. | 8 |
| 33051750 | 2021 | CACNA1B gene variants in adult-onset isolated focal dystonia. | 5 |
| 33360835 | 2021 | Ca(V)2.2 (N-type) voltage-gated calcium channels are activated by SUMOylation pathways. | 2 |
| 34234349 | 2021 | Structure of human Ca(v)2.2 channel blocked by the painkiller ziconotide. | 50 |
| 34731621 | 2021 | Closed-state inactivation and pore-blocker modulation mechanisms of human Ca(V)2.2. | 25 |
| 33051750 | 2021 | CACNA1B gene variants in adult-onset isolated focal dystonia. | 5 |
| 33360835 | 2021 | Ca(V)2.2 (N-type) voltage-gated calcium channels are activated by SUMOylation pathways. | 2 |
| 34234349 | 2021 | Structure of human Ca(v)2.2 channel blocked by the painkiller ziconotide. | 50 |
Citation
Dessen P
CACNA1B (calcium voltage-gated channel subunit alpha1 B)
Atlas Genet Cytogenet Oncol Haematol. 2017-04-01
Online version: http://atlasgeneticsoncology.org/gene/56879/cacna1b-(calcium-voltage-gated-channel-subunit-alpha1-b)
