Identity
HGNC
LOCATION
Xq23
LOCUSID
ALIAS
CHL,MGC1,MGCN,NRLN1,VOPT,dA141H5.1
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 91851
MIM: 300350
HGNC: 29861
Ensembl: ENSG00000101938
Variants:
dbSNP: 91851
ClinVar: 91851
TCGA: ENSG00000101938
COSMIC: CHRDL1
RNA/Proteins
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Signal Transduction | REACTOME | R-HSA-162582 |
| Signaling by BMP | REACTOME | R-HSA-201451 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 35510812 | 2023 | Study on the expression and function of chordin-like 1 in oral squamous cell carcinoma. | 1 |
| 36749222 | 2023 | Bioinformatics identify the role of chordin-like 1 in thyroid cancer. | 0 |
| 35510812 | 2023 | Study on the expression and function of chordin-like 1 in oral squamous cell carcinoma. | 1 |
| 36749222 | 2023 | Bioinformatics identify the role of chordin-like 1 in thyroid cancer. | 0 |
| 28423564 | 2017 | Hypermethylation of the CHRDL1 promoter induces proliferation and metastasis by activating Akt and Erk in gastric cancer. | 29 |
| 28423564 | 2017 | Hypermethylation of the CHRDL1 promoter induces proliferation and metastasis by activating Akt and Erk in gastric cancer. | 29 |
| 26955889 | 2016 | Identification of Human Juvenile Chondrocyte-Specific Factors that Stimulate Stem Cell Growth. | 12 |
| 26976638 | 2016 | Chordin-Like 1 Suppresses Bone Morphogenetic Protein 4-Induced Breast Cancer Cell Migration and Invasion. | 31 |
| 26955889 | 2016 | Identification of Human Juvenile Chondrocyte-Specific Factors that Stimulate Stem Cell Growth. | 12 |
| 26976638 | 2016 | Chordin-Like 1 Suppresses Bone Morphogenetic Protein 4-Induced Breast Cancer Cell Migration and Invasion. | 31 |
| 24073597 | 2015 | X-linked Megalocornea Associated with the Novel CHRDL1 Gene Mutation p.(Pro56Leu*8). | 5 |
| 25712132 | 2015 | Molecular mechanism of CHRDL1-mediated X-linked megalocornea in humans and in Xenopus model. | 14 |
| 26020825 | 2015 | Novel Mutation in the CHRDL1 Gene Detected in Patients With Megalocornea. | 3 |
| 24073597 | 2015 | X-linked Megalocornea Associated with the Novel CHRDL1 Gene Mutation p.(Pro56Leu*8). | 5 |
| 25712132 | 2015 | Molecular mechanism of CHRDL1-mediated X-linked megalocornea in humans and in Xenopus model. | 14 |
Citation
Dessen P
CHRDL1 (chordin like 1)
Atlas Genet Cytogenet Oncol Haematol. 2017-08-01
Online version: http://atlasgeneticsoncology.org/gene/56935/chrdl1-(chordin-like-1)
