Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 28958
MIM: 614775
HGNC: 24990
Ensembl: ENSG00000183978
Variants:
dbSNP: 28958
ClinVar: 28958
TCGA: ENSG00000183978
COSMIC: COA3
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000183978 | ENST00000328434 | Q9Y2R0 |
| ENSG00000183978 | ENST00000328434 | A0A024R1X4 |
| ENSG00000183978 | ENST00000586680 | K7EPV0 |
Expression (GTEx)
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 27791355 | 2016 | Human COA3 Is an Oligomeric Highly Flexible Protein in Solution. | 1 |
| 27791355 | 2016 | Human COA3 Is an Oligomeric Highly Flexible Protein in Solution. | 1 |
| 25604084 | 2015 | Mutations in COA3 cause isolated complex IV deficiency associated with neuropathy, exercise intolerance, obesity, and short stature. | 31 |
| 26358295 | 2015 | COX assembly factor ccdc56 regulates mitochondrial morphology by affecting mitochondrial recruitment of Drp1. | 8 |
| 25604084 | 2015 | Mutations in COA3 cause isolated complex IV deficiency associated with neuropathy, exercise intolerance, obesity, and short stature. | 31 |
| 26358295 | 2015 | COX assembly factor ccdc56 regulates mitochondrial morphology by affecting mitochondrial recruitment of Drp1. | 8 |
| 23362268 | 2013 | hCOA3 stabilizes cytochrome c oxidase 1 (COX1) and promotes cytochrome c oxidase assembly in human mitochondria. | 27 |
| 23362268 | 2013 | hCOA3 stabilizes cytochrome c oxidase 1 (COX1) and promotes cytochrome c oxidase assembly in human mitochondria. | 27 |
| 22356826 | 2012 | Iterative orthology prediction uncovers new mitochondrial proteins and identifies C12orf62 as the human ortholog of COX14, a protein involved in the assembly of cytochrome c oxidase. | 48 |
| 23260140 | 2012 | MITRAC links mitochondrial protein translocation to respiratory-chain assembly and translational regulation. | 95 |
| 22356826 | 2012 | Iterative orthology prediction uncovers new mitochondrial proteins and identifies C12orf62 as the human ortholog of COX14, a protein involved in the assembly of cytochrome c oxidase. | 48 |
| 23260140 | 2012 | MITRAC links mitochondrial protein translocation to respiratory-chain assembly and translational regulation. | 95 |
Citation
Dessen P
COA3 (cytochrome c oxidase assembly factor 3)
Atlas Genet Cytogenet Oncol Haematol. 2017-08-01
Online version: http://atlasgeneticsoncology.org/gene/56952/coa3-(cytochrome-c-oxidase-assembly-factor-3)
