Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 23184
MIM: 607783
HGNC: 13520
Ensembl: ENSG00000117899
Variants:
dbSNP: 23184
ClinVar: 23184
TCGA: ENSG00000117899
COSMIC: MESD
RNA/Proteins
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 33596325 | 2021 | Compound Heterozygous Frameshift Mutations in MESD Cause a Lethal Syndrome Suggestive of Osteogenesis Imperfecta Type XX. | 7 |
| 33596325 | 2021 | Compound Heterozygous Frameshift Mutations in MESD Cause a Lethal Syndrome Suggestive of Osteogenesis Imperfecta Type XX. | 7 |
| 31564437 | 2019 | Autosomal-Recessive Mutations in MESD Cause Osteogenesis Imperfecta. | 26 |
| 31564437 | 2019 | Autosomal-Recessive Mutations in MESD Cause Osteogenesis Imperfecta. | 26 |
| 23469146 | 2013 | The C-terminal region Mesd peptide mimics full-length Mesd and acts as an inhibitor of Wnt/β-catenin signaling in cancer cells. | 9 |
| 23469146 | 2013 | The C-terminal region Mesd peptide mimics full-length Mesd and acts as an inhibitor of Wnt/β-catenin signaling in cancer cells. | 9 |
| 21337463 | 2011 | MESD is essential for apical localization of megalin/LRP2 in the visceral endoderm. | 9 |
| 21397183 | 2011 | Two structural and functional domains of MESD required for proper folding and trafficking of LRP5/6. | 10 |
| 21907199 | 2011 | Mesd is a general inhibitor of different Wnt ligands in Wnt/LRP signaling and inhibits PC-3 tumor growth in vivo. | 20 |
| 21337463 | 2011 | MESD is essential for apical localization of megalin/LRP2 in the visceral endoderm. | 9 |
| 21397183 | 2011 | Two structural and functional domains of MESD required for proper folding and trafficking of LRP5/6. | 10 |
| 21907199 | 2011 | Mesd is a general inhibitor of different Wnt ligands in Wnt/LRP signaling and inhibits PC-3 tumor growth in vivo. | 20 |
| 19746449 | 2009 | A cell-based Dkk1 binding assay reveals roles for extracellular domains of LRP5 in Dkk1 interaction and highlights differences between wild-type and the high bone mass mutant LRP5(G171V). | 3 |
| 19746449 | 2009 | A cell-based Dkk1 binding assay reveals roles for extracellular domains of LRP5 in Dkk1 interaction and highlights differences between wild-type and the high bone mass mutant LRP5(G171V). | 3 |
| 16989816 | 2006 | Modulation of LRP6-mediated Wnt signaling by molecular chaperone Mesd. | 13 |
Citation
Dessen P
MESD (mesoderm development LRP chaperone)
Atlas Genet Cytogenet Oncol Haematol. 2017-08-01
Online version: http://atlasgeneticsoncology.org/gene/56962/mesd-(mesoderm-development-lrp-chaperone)
