INTS10 (integrator complex subunit 10)

2017-08-01  

Identity

HGNC
INTS10
LOCATION
8p21.3
LOCUSID
55174
ALIAS
C8orf35,INT10
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 55174
MIM: 611353
HGNC: 25548
Ensembl: ENSG00000104613

Variants:

dbSNP: 55174
ClinVar: 55174
TCGA: ENSG00000104613
COSMIC: INTS10

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000104613ENST00000397977Q9NVR2
ENSG00000104613ENST00000518424E5RJN5
ENSG00000104613ENST00000518799H0YBH6
ENSG00000104613ENST00000520670H0YBB0
ENSG00000104613ENST00000520827H0YB48
ENSG00000104613ENST00000521008H0YAY7
ENSG00000104613ENST00000521357H0YC09
ENSG00000104613ENST00000522114E5RHN1
ENSG00000104613ENST00000523772H0YB36
ENSG00000104613ENST00000523846H0YBW3
ENSG00000104613ENST00000523869H0YAU7

Expression (GTEx)

0
10
20
30
40
50
60
70
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Gene ExpressionREACTOMER-HSA-74160
RNA polymerase II transcribes snRNA genesREACTOMER-HSA-6807505

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
341337962021Effects of genetic polymorphisms in INTS10 and their interaction with environmental factors on progression from persistent HBV infection to hepatocellular carcinoma.3
341337962021Effects of genetic polymorphisms in INTS10 and their interaction with environmental factors on progression from persistent HBV infection to hepatocellular carcinoma.3
326472232020INTS10-INTS13-INTS14 form a functional module of Integrator that binds nucleic acids and the cleavage module.28
326472232020INTS10-INTS13-INTS14 form a functional module of Integrator that binds nucleic acids and the cleavage module.28
272445552016Genome-wide association study identifies 8p21.3 associated with persistent hepatitis B virus infection among Chinese.35
280273112016Somatic Mutation Patterns in Hemizygous Genomic Regions Unveil Purifying Selection during Tumor Evolution.15
272445552016Genome-wide association study identifies 8p21.3 associated with persistent hepatitis B virus infection among Chinese.35
280273112016Somatic Mutation Patterns in Hemizygous Genomic Regions Unveil Purifying Selection during Tumor Evolution.15

Citation

Dessen P

INTS10 (integrator complex subunit 10)

Atlas Genet Cytogenet Oncol Haematol. 2017-08-01

Online version: http://atlasgeneticsoncology.org/gene/56972/cancer-prone-explorer/humanGenome