Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 9945
MIM: 603865
HGNC: 4242
Ensembl: ENSG00000131459
Variants:
dbSNP: 9945
ClinVar: 9945
TCGA: ENSG00000131459
COSMIC: GFPT2
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000131459 | ENST00000253778 | O94808 |
| ENSG00000131459 | ENST00000253778 | A0A0S2Z4X9 |
| ENSG00000131459 | ENST00000503228 | D6RAC1 |
| ENSG00000131459 | ENST00000518906 | E5RJP4 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36195245 | 2023 | VCAM-1 and GFPT-2: Predictive markers of osteoblast differentiation in human dental pulp stem cells. | 3 |
| 36195245 | 2023 | VCAM-1 and GFPT-2: Predictive markers of osteoblast differentiation in human dental pulp stem cells. | 3 |
| 34923141 | 2022 | Glutamine-Fructose-6-Phosphate Transaminase 2 (GFPT2) Is Upregulated in Breast Epithelial-Mesenchymal Transition and Responds to Oxidative Stress. | 11 |
| 34923141 | 2022 | Glutamine-Fructose-6-Phosphate Transaminase 2 (GFPT2) Is Upregulated in Breast Epithelial-Mesenchymal Transition and Responds to Oxidative Stress. | 11 |
| 33303629 | 2021 | Enzymatic and structural properties of human glutamine:fructose-6-phosphate amidotransferase 2 (hGFAT2). | 9 |
| 33846782 | 2021 | Stomatin‑like protein 2 induces metastasis by regulating the expression of a rate‑limiting enzyme of the hexosamine biosynthetic pathway in pancreatic cancer. | 8 |
| 34735873 | 2021 | Cardiomyocyte protein O-GlcNAcylation is regulated by GFAT1 not GFAT2. | 9 |
| 33303629 | 2021 | Enzymatic and structural properties of human glutamine:fructose-6-phosphate amidotransferase 2 (hGFAT2). | 9 |
| 33846782 | 2021 | Stomatin‑like protein 2 induces metastasis by regulating the expression of a rate‑limiting enzyme of the hexosamine biosynthetic pathway in pancreatic cancer. | 8 |
| 34735873 | 2021 | Cardiomyocyte protein O-GlcNAcylation is regulated by GFAT1 not GFAT2. | 9 |
| 30849544 | 2019 | Identification of a homozygous GFPT2 variant in a family with asthenozoospermia. | 6 |
| 30885209 | 2019 | NF-κB upregulates glutamine-fructose-6-phosphate transaminase 2 to promote migration in non-small cell lung cancer. | 21 |
| 31685298 | 2019 | Glutamine-fructose-6-phosphate transaminase 2 (GFPT2) promotes the EMT of serous ovarian cancer by activating the hexosamine biosynthetic pathway to increase the nuclear location of β-catenin. | 14 |
| 30849544 | 2019 | Identification of a homozygous GFPT2 variant in a family with asthenozoospermia. | 6 |
| 30885209 | 2019 | NF-κB upregulates glutamine-fructose-6-phosphate transaminase 2 to promote migration in non-small cell lung cancer. | 21 |
Citation
Dessen P
GFPT2 (glutamine-fructose-6-phosphate transaminase 2)
Atlas Genet Cytogenet Oncol Haematol. 2017-08-01
Online version: http://atlasgeneticsoncology.org/gene/56981/gfpt2-(glutamine-fructose-6-phosphate-transaminase-2)
