Identity
HGNC
LOCATION
5q14.1
LOCUSID
ALIAS
C5orf12,TPO1
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 256987
MIM: 614551
HGNC: 18825
Ensembl: ENSG00000164300
Variants:
dbSNP: 256987
ClinVar: 256987
TCGA: ENSG00000164300
COSMIC: SERINC5
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000164300 | ENST00000507668 | Q86VE9 |
| ENSG00000164300 | ENST00000509193 | Q86VE9 |
| ENSG00000164300 | ENST00000512972 | Q86VE9 |
| ENSG00000164300 | ENST00000632581 | A0A0J9YYI4 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38400059 | 2024 | Beyond Impairment of Virion Infectivity: New Activities of the Anti-HIV Host Cell Factor SERINC5. | 1 |
| 38400059 | 2024 | Beyond Impairment of Virion Infectivity: New Activities of the Anti-HIV Host Cell Factor SERINC5. | 1 |
| 36577173 | 2023 | Nef enhances HIV-1 replication and infectivity independently of SERINC5 in CEM T cells. | 1 |
| 36622146 | 2023 | AP-2 Adaptor Complex-Dependent Enhancement of HIV-1 Replication by Nef in the Absence of the Nef/AP-2 Targets SERINC5 and CD4. | 0 |
| 36976020 | 2023 | SERINC5 Mediates a Postintegration Block to HIV-1 Gene Expression in Macrophages. | 3 |
| 37768085 | 2023 | Relative resistance of patient-derived envelope sequences to SERINC5-mediated restriction of HIV-1 infectivity. | 2 |
| 36577173 | 2023 | Nef enhances HIV-1 replication and infectivity independently of SERINC5 in CEM T cells. | 1 |
| 36622146 | 2023 | AP-2 Adaptor Complex-Dependent Enhancement of HIV-1 Replication by Nef in the Absence of the Nef/AP-2 Targets SERINC5 and CD4. | 0 |
| 36976020 | 2023 | SERINC5 Mediates a Postintegration Block to HIV-1 Gene Expression in Macrophages. | 3 |
| 37768085 | 2023 | Relative resistance of patient-derived envelope sequences to SERINC5-mediated restriction of HIV-1 infectivity. | 2 |
| 35893701 | 2022 | SERINC5-Mediated Restriction of HIV-1 Infectivity Correlates with Resistance to Cholesterol Extraction but Not with Lipid Order of Viral Membrane. | 4 |
| 36409124 | 2022 | Restriction of Influenza A Virus by SERINC5. | 6 |
| 35893701 | 2022 | SERINC5-Mediated Restriction of HIV-1 Infectivity Correlates with Resistance to Cholesterol Extraction but Not with Lipid Order of Viral Membrane. | 4 |
| 36409124 | 2022 | Restriction of Influenza A Virus by SERINC5. | 6 |
| 33597208 | 2021 | SERINC5 Can Enhance Proinflammatory Cytokine Production by Primary Human Myeloid Cells in Response to Challenge with HIV-1 Particles. | 7 |
Citation
Dessen P
SERINC5 (serine incorporator 5)
Atlas Genet Cytogenet Oncol Haematol. 2017-08-01
Online version: http://atlasgeneticsoncology.org/gene/57005/serinc5-(serine-incorporator-5)
