Identity
HGNC
LOCATION
11q13.5
LOCUSID
ALIAS
ARAT,GS1999FULL,HMFN1045
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 84649
MIM: 606983
HGNC: 16940
Ensembl: ENSG00000062282
Variants:
dbSNP: 84649
ClinVar: 84649
TCGA: ENSG00000062282
COSMIC: DGAT2
RNA/Proteins
Expression (GTEx)
Pathways
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38500157 | 2024 | The role of DGAT1 and DGAT2 in regulating tumor cell growth and their potential clinical implications. | 2 |
| 38500157 | 2024 | The role of DGAT1 and DGAT2 in regulating tumor cell growth and their potential clinical implications. | 2 |
| 37516308 | 2023 | Preferential lipolysis of DGAT1 over DGAT2 generated triacylglycerol in Huh7 hepatocytes. | 1 |
| 37779421 | 2023 | The roles of DGAT1 and DGAT2 in human myotubes are dependent on donor patho-physiological background. | 1 |
| 37516308 | 2023 | Preferential lipolysis of DGAT1 over DGAT2 generated triacylglycerol in Huh7 hepatocytes. | 1 |
| 37779421 | 2023 | The roles of DGAT1 and DGAT2 in human myotubes are dependent on donor patho-physiological background. | 1 |
| 35232775 | 2022 | DGAT2 Inhibition Potentiates Lipid Droplet Formation To Reduce Cytotoxicity in APOL1 Kidney Risk Variants. | 13 |
| 35232775 | 2022 | DGAT2 Inhibition Potentiates Lipid Droplet Formation To Reduce Cytotoxicity in APOL1 Kidney Risk Variants. | 13 |
| 34635855 | 2021 | ACC inhibitor alone or co-administered with a DGAT2 inhibitor in patients with non-alcoholic fatty liver disease: two parallel, placebo-controlled, randomized phase 2a trials. | 58 |
| 34635855 | 2021 | ACC inhibitor alone or co-administered with a DGAT2 inhibitor in patients with non-alcoholic fatty liver disease: two parallel, placebo-controlled, randomized phase 2a trials. | 58 |
| 32506038 | 2020 | Obesity promotes gastric cancer metastasis via diacylglycerol acyltransferase 2-dependent lipid droplets accumulation and redox homeostasis. | 25 |
| 32506038 | 2020 | Obesity promotes gastric cancer metastasis via diacylglycerol acyltransferase 2-dependent lipid droplets accumulation and redox homeostasis. | 25 |
| 31078041 | 2019 | Dgat2 reduces hepatocellular carcinoma malignancy via downregulation of cell cycle-related gene expression. | 11 |
| 31078041 | 2019 | Dgat2 reduces hepatocellular carcinoma malignancy via downregulation of cell cycle-related gene expression. | 11 |
| 29604290 | 2018 | Intestinal Failure and Aberrant Lipid Metabolism in Patients With DGAT1 Deficiency. | 46 |
Citation
Dessen P
DGAT2 (diacylglycerol O-acyltransferase 2)
Atlas Genet Cytogenet Oncol Haematol. 2017-08-01
Online version: http://atlasgeneticsoncology.org/gene/57006/dgat2-(diacylglycerol-o-acyltransferase-2)
