CTDSP1 (CTD small phosphatase 1)

2017-08-01  

Identity

HGNC
CTDSP1
LOCATION
2q35
LOCUSID
58190
ALIAS
NIF3,NLI-IF,NLIIF,SCP1
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 58190
MIM: 605323
HGNC: 21614
Ensembl: ENSG00000144579

Variants:

dbSNP: 58190
ClinVar: 58190
TCGA: ENSG00000144579
COSMIC: CTDSP1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000144579ENST00000273062Q9GZU7
ENSG00000144579ENST00000273062A0A024R461
ENSG00000144579ENST00000428361H7C1Z7
ENSG00000144579ENST00000431127H7C3E0
ENSG00000144579ENST00000443891Q9GZU7
ENSG00000144579ENST00000452977H7C270

Expression (GTEx)

0
50
100
150
200
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

References

Pubmed IDYearTitleCitations
340790822021GPC5 suppresses lung cancer progression and metastasis via intracellular CTDSP1/AhR/ARNT signaling axis and extracellular exosome secretion.7
342620562021C-terminal domain small phosphatase 1 (CTDSP1) regulates growth factor expression and axonal regeneration in peripheral nerve tissue.5
340790822021GPC5 suppresses lung cancer progression and metastasis via intracellular CTDSP1/AhR/ARNT signaling axis and extracellular exosome secretion.7
342620562021C-terminal domain small phosphatase 1 (CTDSP1) regulates growth factor expression and axonal regeneration in peripheral nerve tissue.5
329733322020Deubiquitinase USP29 promotes gastric cancer cell migration by cooperating with phosphatase SCP1 to stabilize Snail protein.33
329733322020Deubiquitinase USP29 promotes gastric cancer cell migration by cooperating with phosphatase SCP1 to stabilize Snail protein.33
317749102019Tumor suppressor properties of the small C-terminal domain phosphatases in non-small cell lung cancer.8
317749102019Tumor suppressor properties of the small C-terminal domain phosphatases in non-small cell lung cancer.8
302178182018Phosphatase activity of small C-terminal domain phosphatase 1 (SCP1) controls the stability of the key neuronal regulator RE1-silencing transcription factor (REST).10
302178182018Phosphatase activity of small C-terminal domain phosphatase 1 (SCP1) controls the stability of the key neuronal regulator RE1-silencing transcription factor (REST).10
258933002016SCP1 regulates c-Myc stability and functions through dephosphorylating c-Myc Ser62.18
269753712016The Small C-terminal Domain Phosphatase 1 Inhibits Cancer Cell Migration and Invasion by Dephosphorylating Ser(P)68-Twist1 to Accelerate Twist1 Protein Degradation.18
27751849201627-Hydroxycholesterol increases Myc protein stability via suppressing PP2A, SCP1 and FBW7 transcription in MCF-7 breast cancer cells.6
258933002016SCP1 regulates c-Myc stability and functions through dephosphorylating c-Myc Ser62.18
269753712016The Small C-terminal Domain Phosphatase 1 Inhibits Cancer Cell Migration and Invasion by Dephosphorylating Ser(P)68-Twist1 to Accelerate Twist1 Protein Degradation.18

Citation

Dessen P

CTDSP1 (CTD small phosphatase 1)

Atlas Genet Cytogenet Oncol Haematol. 2017-08-01

Online version: http://atlasgeneticsoncology.org/gene/57009/teaching-explorer/submit-meetings/