HS6ST3 (heparan sulfate 6-O-sulfotransferase 3)

2017-08-01  

Identity

HGNC
LOCATION
13q32.1
LOCUSID
ALIAS
HS6ST-3
FUSION GENES

Other Information

Locus ID:

NCBI: 266722
MIM: 609401
HGNC: 19134
Ensembl: ENSG00000185352

Variants:

dbSNP: 266722
ClinVar: 266722
TCGA: ENSG00000185352
COSMIC: HS6ST3

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000185352ENST00000376705Q8IZP7
ENSG00000185352ENST00000620595A0A087X0G1

Expression (GTEx)

0
5
10
15
20
25

Pathways

PathwaySourceExternal ID
Glycosaminoglycan biosynthesis - heparan sulfate / heparinKEGGko00534
Glycosaminoglycan biosynthesis - heparan sulfate / heparinKEGGhsa00534
MetabolismREACTOMER-HSA-1430728
Metabolism of carbohydratesREACTOMER-HSA-71387
Glycosaminoglycan metabolismREACTOMER-HSA-1630316
Heparan sulfate/heparin (HS-GAG) metabolismREACTOMER-HSA-1638091
HS-GAG biosynthesisREACTOMER-HSA-2022928

References

Pubmed IDYearTitleCitations
280177272017Silencing HS6ST3 inhibits growth and progression of breast cancer cells through suppressing IGF1R and inducing XAF1.9
280177272017Silencing HS6ST3 inhibits growth and progression of breast cancer cells through suppressing IGF1R and inducing XAF1.9
243711612013Association of HS6ST3 gene polymorphisms with obesity and triglycerides: gene x gender interaction.4
243711612013Association of HS6ST3 gene polymorphisms with obesity and triglycerides: gene x gender interaction.4
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.78
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.78

Citation

Dessen P

HS6ST3 (heparan sulfate 6-O-sulfotransferase 3)

Atlas Genet Cytogenet Oncol Haematol. 2017-08-01

Online version: http://atlasgeneticsoncology.org/gene/57012/hs6st3-(heparan-sulfate-6-o-sulfotransferase-3)