Identity
HGNC
LOCATION
4q35.1
LOCUSID
ALIAS
CCDC111,MYP22,Primpol1
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 201973
MIM: 615421
HGNC: 26575
Ensembl: ENSG00000164306
Variants:
dbSNP: 201973
ClinVar: 201973
TCGA: ENSG00000164306
COSMIC: PRIMPOL
RNA/Proteins
Expression (GTEx)
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37971291 | 2024 | PRIMPOL ensures robust handoff between on-the-fly and post-replicative DNA lesion bypass. | 0 |
| 38180818 | 2024 | USP1-dependent nucleolytic expansion of PRIMPOL-generated nascent DNA strand discontinuities during replication stress. | 3 |
| 38492718 | 2024 | PrimPol Variant V102A with Altered Primase and Polymerase Activities. | 0 |
| 37971291 | 2024 | PRIMPOL ensures robust handoff between on-the-fly and post-replicative DNA lesion bypass. | 0 |
| 38180818 | 2024 | USP1-dependent nucleolytic expansion of PRIMPOL-generated nascent DNA strand discontinuities during replication stress. | 3 |
| 38492718 | 2024 | PrimPol Variant V102A with Altered Primase and Polymerase Activities. | 0 |
| 37326028 | 2023 | The role of catalytic and regulatory domains of human PrimPol in DNA binding and synthesis. | 2 |
| 37758313 | 2023 | Regulation of Human DNA Primase-Polymerase PrimPol. | 0 |
| 38105210 | 2023 | Response of PRIMPOL-Knockout Human Lung Adenocarcinoma A549 Cells to Genotoxic Stress. | 0 |
| 38203225 | 2023 | 3'dNTP Binding Is Modulated during Primer Synthesis and Translesion by Human PrimPol. | 0 |
| 37326028 | 2023 | The role of catalytic and regulatory domains of human PrimPol in DNA binding and synthesis. | 2 |
| 37758313 | 2023 | Regulation of Human DNA Primase-Polymerase PrimPol. | 0 |
| 38105210 | 2023 | Response of PRIMPOL-Knockout Human Lung Adenocarcinoma A549 Cells to Genotoxic Stress. | 0 |
| 38203225 | 2023 | 3'dNTP Binding Is Modulated during Primer Synthesis and Translesion by Human PrimPol. | 0 |
| 36647718 | 2022 | PRIMPOL competes with RAD51 to resolve G-quadruplex-induced replication stress via its interaction with RPA. | 1 |
Citation
Dessen P
PRIMPOL (primase and DNA directed polymerase)
Atlas Genet Cytogenet Oncol Haematol. 2017-08-01
Online version: http://atlasgeneticsoncology.org/gene/57026/new-content/
