Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 59352
MIM: 606653
HGNC: 19719
Ensembl: ENSG00000133067
Variants:
dbSNP: 59352
ClinVar: 59352
TCGA: ENSG00000133067
COSMIC: LGR6
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38014454 | 2024 | The oncogenic role of LGR6 overexpression induced by aberrant Wnt/β-catenin signaling in lung cancer. | 1 |
| 38014454 | 2024 | The oncogenic role of LGR6 overexpression induced by aberrant Wnt/β-catenin signaling in lung cancer. | 1 |
| 37770230 | 2023 | WNT enhancing signals in pancreatic cancer are transmitted by LGR6. | 0 |
| 37802707 | 2023 | DNA methylation and expression of LGR6 gene in ankylosing spondylitis: A case-control study. | 0 |
| 37770230 | 2023 | WNT enhancing signals in pancreatic cancer are transmitted by LGR6. | 0 |
| 37802707 | 2023 | DNA methylation and expression of LGR6 gene in ankylosing spondylitis: A case-control study. | 0 |
| 34489551 | 2021 | LGR6 activates the Wnt/β-catenin signaling pathway and forms a β-catenin/TCF7L2/LGR6 feedback loop in LGR6(high) cervical cancer stem cells. | 8 |
| 34494532 | 2021 | [Expression and Significance of Leucine-rich Repeat-containing G-protein Coupled Receptor 5/6 in Wnt Pathway in Children with Acute Lymphoblastic Leukemia]. | 0 |
| 34943945 | 2021 | Increased LGR6 Expression Sustains Long-Term Wnt Activation and Acquisition of Senescence in Epithelial Progenitors in Chronic Lung Diseases. | 4 |
| 34489551 | 2021 | LGR6 activates the Wnt/β-catenin signaling pathway and forms a β-catenin/TCF7L2/LGR6 feedback loop in LGR6(high) cervical cancer stem cells. | 8 |
| 34494532 | 2021 | [Expression and Significance of Leucine-rich Repeat-containing G-protein Coupled Receptor 5/6 in Wnt Pathway in Children with Acute Lymphoblastic Leukemia]. | 0 |
| 34943945 | 2021 | Increased LGR6 Expression Sustains Long-Term Wnt Activation and Acquisition of Senescence in Epithelial Progenitors in Chronic Lung Diseases. | 4 |
| 31917882 | 2020 | LGR6 is a potential diagnostic and prognostic marker for esophageal squamous cell carcinoma. | 6 |
| 32244172 | 2020 | Epithelial stem cell marker LGR6 expression identifies a low-risk subgroup in human papillomavirus positive oropharyngeal squamous cell carcinoma. | 2 |
| 33109540 | 2020 | WNT Signaling Driven by R-spondin 1 and LGR6 in High-grade Serous Ovarian Cancer. | 4 |
Citation
Dessen P
LGR6 (leucine rich repeat containing G protein-coupled receptor 6)
Atlas Genet Cytogenet Oncol Haematol. 2017-08-01
Online version: http://atlasgeneticsoncology.org/gene/57032/lgr6-(leucine-rich-repeat-containing-g-protein-coupled-receptor-6)
