Identity
HGNC
LOCATION
14q21.3
LOCUSID
ALIAS
MAMDC1,c14_5286
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 161357
MIM: 611128
HGNC: 19835
Ensembl: ENSG00000139915
Variants:
dbSNP: 161357
ClinVar: 161357
TCGA: ENSG00000139915
COSMIC: MDGA2
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA164752812 | milnacipran | Chemical | ClinicalAnnotation | associated | PD | 22445761 | |
| PA447321 | Depressive Disorder, Major | Disease | ClinicalAnnotation | associated | PD | 22445761 | |
| PA449690 | fluvoxamine | Chemical | ClinicalAnnotation | associated | PD | 22445761 | |
| PA450801 | paroxetine | Chemical | ClinicalAnnotation | associated | PD | 22445761 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 26206665 | 2016 | MDGA2 is a novel tumour suppressor cooperating with DMAP1 in gastric cancer and is associated with disease outcome. | 33 |
| 26206665 | 2016 | MDGA2 is a novel tumour suppressor cooperating with DMAP1 in gastric cancer and is associated with disease outcome. | 33 |
| 21399569 | 2011 | Evidence for associations between MDGA2 polymorphisms and harm avoidance: replication and extension of a genome-wide association finding. | 2 |
| 21542908 | 2011 | Rostral growth of commissural axons requires the cell adhesion molecule MDGA2. | 12 |
| 21660437 | 2011 | Single-nucleotide polymorphisms of MAMDC1 are associated with rash and photosensitivity, but not disease risk, of systemic lupus erythematosus in Chinese mainland population. | 1 |
| 21399569 | 2011 | Evidence for associations between MDGA2 polymorphisms and harm avoidance: replication and extension of a genome-wide association finding. | 2 |
| 21542908 | 2011 | Rostral growth of commissural axons requires the cell adhesion molecule MDGA2. | 12 |
| 21660437 | 2011 | Single-nucleotide polymorphisms of MAMDC1 are associated with rash and photosensitivity, but not disease risk, of systemic lupus erythematosus in Chinese mainland population. | 1 |
| 20379614 | 2010 | Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. | 78 |
| 20628086 | 2010 | Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study. | 15 |
| 20379614 | 2010 | Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. | 78 |
| 20628086 | 2010 | Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study. | 15 |
| 19440164 | 2009 | Follow-up association study of novel neuroticism gene MAMDC1. | 5 |
| 19557195 | 2009 | Genome-wide analyses of exonic copy number variants in a family-based study point to novel autism susceptibility genes. | 206 |
| 19913121 | 2009 | Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip. | 105 |
Citation
Dessen P
MDGA2 (MAM domain containing glycosylphosphatidylinositol anchor 2)
Atlas Genet Cytogenet Oncol Haematol. 2017-08-01
Online version: http://atlasgeneticsoncology.org/gene/57033/mdga2-(mam-domain-containing-glycosylphosphatidylinositol-anchor-2)
