Identity
HGNC
LOCATION
17q25.1
LOCUSID
ALIAS
DFNB107,GRAMD6,WBP-2
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 23558
MIM: 606962
HGNC: 12738
Ensembl: ENSG00000132471
Variants:
dbSNP: 23558
ClinVar: 23558
TCGA: ENSG00000132471
COSMIC: WBP2
RNA/Proteins
Expression (GTEx)
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 34197030 | 2022 | WBP2 promotes BTRC mRNA stability to drive migration and invasion in triple-negative breast cancer via NF-κB activation. | 11 |
| 34197030 | 2022 | WBP2 promotes BTRC mRNA stability to drive migration and invasion in triple-negative breast cancer via NF-κB activation. | 11 |
| 33475198 | 2021 | WBP2 promotes gastric cancer cell migration via novel targeting of LATS2 kinase in the Hippo tumor suppressor pathway. | 8 |
| 33658485 | 2021 | WW domain-binding protein 2 overexpression prevents diet-induced liver steatosis and insulin resistance through AMPKβ1. | 5 |
| 33837178 | 2021 | WBP2 negatively regulates the Hippo pathway by competitively binding to WWC3 with LATS1 to promote non-small cell lung cancer progression. | 5 |
| 34117091 | 2021 | WBP2 inhibits microRNA biogenesis via interaction with the microprocessor complex. | 4 |
| 33475198 | 2021 | WBP2 promotes gastric cancer cell migration via novel targeting of LATS2 kinase in the Hippo tumor suppressor pathway. | 8 |
| 33658485 | 2021 | WW domain-binding protein 2 overexpression prevents diet-induced liver steatosis and insulin resistance through AMPKβ1. | 5 |
| 33837178 | 2021 | WBP2 negatively regulates the Hippo pathway by competitively binding to WWC3 with LATS1 to promote non-small cell lung cancer progression. | 5 |
| 34117091 | 2021 | WBP2 inhibits microRNA biogenesis via interaction with the microprocessor complex. | 4 |
| 32393834 | 2020 | The emerging roles of WBP2 oncogene in human cancers. | 14 |
| 32393834 | 2020 | The emerging roles of WBP2 oncogene in human cancers. | 14 |
| 30593516 | 2019 | Elevated WBP2 Expression in HER2-positive Breast Cancers Correlates with Sensitivity to Trastuzumab-based Neoadjuvant Therapy: A Retrospective and Multicentric Study. | 10 |
| 30593516 | 2019 | Elevated WBP2 Expression in HER2-positive Breast Cancers Correlates with Sensitivity to Trastuzumab-based Neoadjuvant Therapy: A Retrospective and Multicentric Study. | 10 |
| 29497031 | 2018 | WW domain-binding protein 2 acts as an oncogene by modulating the activity of the glycolytic enzyme ENO1 in glioma. | 34 |
Citation
Dessen P
WBP2 (WW domain binding protein 2)
Atlas Genet Cytogenet Oncol Haematol. 2017-08-01
Online version: http://atlasgeneticsoncology.org/gene/57045/wbp2-(ww-domain-binding-protein-2)
