USP26 (ubiquitin specific peptidase 26)

2017-08-01  

Identity

HGNC
LOCATION
Xq26.2
LOCUSID

Other Information

Locus ID:

NCBI: 83844
MIM: 300309
HGNC: 13485
Ensembl: ENSG00000134588

Variants:

dbSNP: 83844
ClinVar: 83844
TCGA: ENSG00000134588
COSMIC: USP26

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000134588ENST00000370832Q9BXU7
ENSG00000134588ENST00000511190Q9BXU7

Expression (GTEx)

0
1

Pathways

PathwaySourceExternal ID
Metabolism of proteinsREACTOMER-HSA-392499
Post-translational protein modificationREACTOMER-HSA-597592
DeubiquitinationREACTOMER-HSA-5688426
Ub-specific processing proteasesREACTOMER-HSA-5689880

References

Pubmed IDYearTitleCitations
380648512024Machine learning-based classification of deubiquitinase USP26 and its cell proliferation inhibition through stabilizing KLF6 in cervical cancer.1
380648512024Machine learning-based classification of deubiquitinase USP26 and its cell proliferation inhibition through stabilizing KLF6 in cervical cancer.1
350749402022The association between mutations in ubiquitin-specific protease 26 (USP26) and male infertility: a systematic review and meta-analysis.1
353976262022USP26 promotes anaplastic thyroid cancer progression by stabilizing TAZ.7
358576302022An RNF12-USP26 amplification loop drives germ cell specification and is disrupted by disease-associated mutations.3
350749402022The association between mutations in ubiquitin-specific protease 26 (USP26) and male infertility: a systematic review and meta-analysis.1
353976262022USP26 promotes anaplastic thyroid cancer progression by stabilizing TAZ.7
358576302022An RNF12-USP26 amplification loop drives germ cell specification and is disrupted by disease-associated mutations.3
339782332021Paternal USP26 mutations raise Klinefelter syndrome risk in the offspring of mice and humans.8
342020842021Novel Mutations in X-Linked, USP26-Induced Asthenoteratozoospermia and Male Infertility.6
339782332021Paternal USP26 mutations raise Klinefelter syndrome risk in the offspring of mice and humans.8
342020842021Novel Mutations in X-Linked, USP26-Induced Asthenoteratozoospermia and Male Infertility.6
308871152019Ubiquitin-specific protease 26 (USP26) is not essential for mouse gametogenesis and fertility.16
308871152019Ubiquitin-specific protease 26 (USP26) is not essential for mouse gametogenesis and fertility.16
278103592017The testis-specific USP26 is a deubiquitinating enzyme of the ubiquitin ligase Mdm2.11

Citation

Dessen P

USP26 (ubiquitin specific peptidase 26)

Atlas Genet Cytogenet Oncol Haematol. 2017-08-01

Online version: http://atlasgeneticsoncology.org/gene/57046/usp26-(ubiquitin-specific-peptidase-26)