Identity
HGNC
LOCATION
1p13.3
LOCUSID
ALIAS
C1orf30,HKSHIIIC,KSHIIIC,KV3.4
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 3749
MIM: 176265
HGNC: 6236
Ensembl: ENSG00000116396
Variants:
dbSNP: 3749
ClinVar: 3749
TCGA: ENSG00000116396
COSMIC: KCNC4
RNA/Proteins
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Neuronal System | REACTOME | R-HSA-112316 |
| Potassium Channels | REACTOME | R-HSA-1296071 |
| Voltage gated Potassium channels | REACTOME | R-HSA-1296072 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36198500 | 2022 | Tunable Action Potential Repolarization Governed by Kv3.4 Channels in Dorsal Root Ganglion Neurons. | 3 |
| 36198500 | 2022 | Tunable Action Potential Repolarization Governed by Kv3.4 Channels in Dorsal Root Ganglion Neurons. | 3 |
| 33368632 | 2021 | PKCε associates with the Kv3.4 channel to promote its expression in a kinase activity-dependent manner. | 1 |
| 33368632 | 2021 | PKCε associates with the Kv3.4 channel to promote its expression in a kinase activity-dependent manner. | 1 |
| 31471334 | 2019 | HIF-1α Regulates Proliferation and Invasion of Oral Cancer Cells through Kv3.4 Channel. | 9 |
| 31471334 | 2019 | HIF-1α Regulates Proliferation and Invasion of Oral Cancer Cells through Kv3.4 Channel. | 9 |
| 26648458 | 2016 | Expression of the voltage-gated potassium channel Kv3.4 in oral leucoplakias and oral squamous cell carcinomas. | 5 |
| 26648458 | 2016 | Expression of the voltage-gated potassium channel Kv3.4 in oral leucoplakias and oral squamous cell carcinomas. | 5 |
| 25609640 | 2015 | Dysregulation of Kv3.4 channels in dorsal root ganglia following spinal cord injury. | 33 |
| 25609640 | 2015 | Dysregulation of Kv3.4 channels in dorsal root ganglia following spinal cord injury. | 33 |
| 23443853 | 2013 | Kv3.4 potassium channel-mediated electrosignaling controls cell cycle and survival of irradiated leukemia cells. | 16 |
| 23443853 | 2013 | Kv3.4 potassium channel-mediated electrosignaling controls cell cycle and survival of irradiated leukemia cells. | 16 |
| 21912965 | 2012 | Brain expression of Kv3 subunits during development, adulthood and aging and in a murine model of Alzheimer's disease. | 19 |
| 22473424 | 2012 | Coexpression of high-voltage-activated ion channels Kv3.4 and Cav1.2 in pioneer axons during pathfinding in the developing rat forebrain. | 10 |
| 21912965 | 2012 | Brain expression of Kv3 subunits during development, adulthood and aging and in a murine model of Alzheimer's disease. | 19 |
Citation
Dessen P
KCNC4 (potassium voltage-gated channel subfamily C member 4)
Atlas Genet Cytogenet Oncol Haematol. 2017-08-01
Online version: http://atlasgeneticsoncology.org/gene/57047/kcnc4-(potassium-voltage-gated-channel-subfamily-c-member-4)
