WFIKKN1 (WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 1)

2017-10-01  

Identity

HGNC
LOCATION
16p13.3
LOCUSID
ALIAS
C16orf12,RJD2,WFDC20A,WFIKKN

Other Information

Locus ID:

NCBI: 117166
MIM: 608021
HGNC: 30912
Ensembl: ENSG00000127578

Variants:

dbSNP: 117166
ClinVar: 117166
TCGA: ENSG00000127578
COSMIC: WFIKKN1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000127578ENST00000319070Q96NZ8

Expression (GTEx)

0
5
10
15
20
25

References

Pubmed IDYearTitleCitations
273254602016WFIKKN1 and WFIKKN2: "Companion" proteins regulating TGFB activity.11
277823772016Influence of WFIKKN1 on BMP1-mediated activation of latent myostatin.2
273254602016WFIKKN1 and WFIKKN2: "Companion" proteins regulating TGFB activity.11
277823772016Influence of WFIKKN1 on BMP1-mediated activation of latent myostatin.2
238296722013Latent myostatin has significant activity and this activity is controlled more efficiently by WFIKKN1 than by WFIKKN2.11
238296722013Latent myostatin has significant activity and this activity is controlled more efficiently by WFIKKN1 than by WFIKKN2.11
210547892010WFIKKN1 and WFIKKN2 bind growth factors TGFβ1, BMP2 and BMP4 but do not inhibit their signalling activity.22
210547892010WFIKKN1 and WFIKKN2 bind growth factors TGFβ1, BMP2 and BMP4 but do not inhibit their signalling activity.22
185960302008Both WFIKKN1 and WFIKKN2 have high affinity for growth and differentiation factors 8 and 11.43
185960302008Both WFIKKN1 and WFIKKN2 have high affinity for growth and differentiation factors 8 and 11.43
167917412006Second Kunitz-type protease inhibitor domain of the human WFIKKN1 protein.3
167917412006Second Kunitz-type protease inhibitor domain of the human WFIKKN1 protein.3
127090702003Expression, purification and characterization of the second Kunitz-type protease inhibitor domain of the human WFIKKN protein.5
127090702003Expression, purification and characterization of the second Kunitz-type protease inhibitor domain of the human WFIKKN protein.5
119288172002Distinct expression pattern of two related human proteins containing multiple types of protease-inhibitory modules.15

Citation

Dessen P

WFIKKN1 (WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 1)

Atlas Genet Cytogenet Oncol Haematol. 2017-10-01

Online version: http://atlasgeneticsoncology.org/gene/57054/