Identity
HGNC
LOCATION
14q24.2
LOCUSID
ALIAS
WDR21,WDR21A
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 26094
MIM: 616372
HGNC: 20229
Ensembl: ENSG00000119599
Variants:
dbSNP: 26094
ClinVar: 26094
TCGA: ENSG00000119599
COSMIC: DCAF4
RNA/Proteins
Expression (GTEx)
Protein levels (Protein atlas)
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA10832 | corticosteroids | Chemical | ClinicalAnnotation | associated | PD | 22366774 | |
| PA443450 | Asthma | Disease | ClinicalAnnotation | associated | PD | 22366774 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 28383684 | 2017 | Functional variants in DCAF4 associated with lung cancer risk in European populations. | 11 |
| 28383684 | 2017 | Functional variants in DCAF4 associated with lung cancer risk in European populations. | 11 |
| 25624462 | 2015 | DCAF4, a novel gene associated with leucocyte telomere length. | 44 |
| 25624462 | 2015 | DCAF4, a novel gene associated with leucocyte telomere length. | 44 |
| 22366774 | 2012 | Association between WDR21A polymorphisms and airway responsiveness to inhaled corticosteroids in asthmatic patients. | 1 |
| 22366774 | 2012 | Association between WDR21A polymorphisms and airway responsiveness to inhaled corticosteroids in asthmatic patients. | 1 |
Citation
Dessen P
DCAF4 (DDB1 and CUL4 associated factor 4)
Atlas Genet Cytogenet Oncol Haematol. 2017-10-01
Online version: http://atlasgeneticsoncology.org/gene/57059/submit-meetings/gene-explorer/
