Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 8685
MIM: 604870
HGNC: 6895
Ensembl: ENSG00000019169
Variants:
dbSNP: 8685
ClinVar: 8685
TCGA: ENSG00000019169
COSMIC: MARCO
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000019169 | ENST00000327097 | Q9UEW3 |
| ENSG00000019169 | ENST00000327097 | Q4ZG40 |
| ENSG00000019169 | ENST00000412481 | C9JKT8 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37212598 | 2023 | Cancer Cells Promote Immune Regulatory Function of Macrophages by Upregulating Scavenger Receptor MARCO Expression. | 5 |
| 37212598 | 2023 | Cancer Cells Promote Immune Regulatory Function of Macrophages by Upregulating Scavenger Receptor MARCO Expression. | 5 |
| 35364781 | 2022 | Association of the MARCO polymorphism rs6761637 with hepatocellular carcinoma susceptibility and clinical characteristics. | 2 |
| 35364781 | 2022 | Association of the MARCO polymorphism rs6761637 with hepatocellular carcinoma susceptibility and clinical characteristics. | 2 |
| 33293426 | 2021 | Targeting MARCO and IL37R on Immunosuppressive Macrophages in Lung Cancer Blocks Regulatory T Cells and Supports Cytotoxic Lymphocyte Function. | 78 |
| 34011400 | 2021 | Single-cell characterization of macrophages in glioblastoma reveals MARCO as a mesenchymal pro-tumor marker. | 40 |
| 34398403 | 2021 | TLR2 Potentiates SR-Marco-Mediated Neuroinflammation by Interacting with the SRCR Domain. | 5 |
| 34626585 | 2021 | Scavenger receptor MARCO contributes to macrophage phagocytosis and clearance of tumor cells. | 14 |
| 33293426 | 2021 | Targeting MARCO and IL37R on Immunosuppressive Macrophages in Lung Cancer Blocks Regulatory T Cells and Supports Cytotoxic Lymphocyte Function. | 78 |
| 34011400 | 2021 | Single-cell characterization of macrophages in glioblastoma reveals MARCO as a mesenchymal pro-tumor marker. | 40 |
| 34398403 | 2021 | TLR2 Potentiates SR-Marco-Mediated Neuroinflammation by Interacting with the SRCR Domain. | 5 |
| 34626585 | 2021 | Scavenger receptor MARCO contributes to macrophage phagocytosis and clearance of tumor cells. | 14 |
| 32740454 | 2020 | Genetic Susceptibility to Life-threatening Respiratory Syncytial Virus Infection in Previously Healthy Infants. | 3 |
| 33311558 | 2020 | Scavenger receptor MARCO contributes to cellular internalization of exosomes by dynamin-dependent endocytosis and macropinocytosis. | 20 |
| 33363539 | 2020 | Binding of Macrophage Receptor MARCO, LDL, and LDLR to Disease-Associated Crystalline Structures. | 6 |
Citation
Dessen P
MARCO (macrophage receptor with collagenous structure)
Atlas Genet Cytogenet Oncol Haematol. 2017-10-01
Online version: http://atlasgeneticsoncology.org/gene/57064/marco-(macrophage-receptor-with-collagenous-structure)
