Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 4741
MIM: 162250
HGNC: 7734
Ensembl: ENSG00000104722
Variants:
dbSNP: 4741
ClinVar: 4741
TCGA: ENSG00000104722
COSMIC: NEFM
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000104722 | ENST00000221166 | P07197 |
| ENSG00000104722 | ENST00000433454 | P07197 |
| ENSG00000104722 | ENST00000437366 | E7ESP9 |
| ENSG00000104722 | ENST00000518131 | E7EMV2 |
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Amyotrophic lateral sclerosis (ALS) | KEGG | ko05014 |
| Amyotrophic lateral sclerosis (ALS) | KEGG | hsa05014 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36200879 | 2023 | Neurodegeneration Markers in the Cerebrospinal Fluid of 100 Patients with Schizophrenia Spectrum Disorder. | 2 |
| 36200879 | 2023 | Neurodegeneration Markers in the Cerebrospinal Fluid of 100 Patients with Schizophrenia Spectrum Disorder. | 2 |
| 34001208 | 2021 | NEFM DNA methylation correlates with immune infiltration and survival in breast cancer. | 19 |
| 34001208 | 2021 | NEFM DNA methylation correlates with immune infiltration and survival in breast cancer. | 19 |
| 32450002 | 2020 | LINC00294 negatively modulates cell proliferation in glioma through a neurofilament medium-mediated pathway via interacting with miR-1278. | 13 |
| 32450002 | 2020 | LINC00294 negatively modulates cell proliferation in glioma through a neurofilament medium-mediated pathway via interacting with miR-1278. | 13 |
| 30029677 | 2018 | Dysregulation of human NEFM and NEFH mRNA stability by ALS-linked miRNAs. | 20 |
| 30029677 | 2018 | Dysregulation of human NEFM and NEFH mRNA stability by ALS-linked miRNAs. | 20 |
| 28584012 | 2017 | NEFM (Neurofilament Medium) Polypeptide, a Marker for Zona Glomerulosa Cells in Human Adrenal, Inhibits D1R (Dopamine D1 Receptor)-Mediated Secretion of Aldosterone. | 13 |
| 28634551 | 2017 | Mechanisms and Consequences of Dopamine Depletion-Induced Attenuation of the Spinophilin/Neurofilament Medium Interaction. | 10 |
| 28584012 | 2017 | NEFM (Neurofilament Medium) Polypeptide, a Marker for Zona Glomerulosa Cells in Human Adrenal, Inhibits D1R (Dopamine D1 Receptor)-Mediated Secretion of Aldosterone. | 13 |
| 28634551 | 2017 | Mechanisms and Consequences of Dopamine Depletion-Induced Attenuation of the Spinophilin/Neurofilament Medium Interaction. | 10 |
| 24636402 | 2014 | Elevated levels of autoantibodies targeting the M1 muscarinic acetylcholine receptor and neurofilament medium in sera from subgroups of patients with schizophrenia. | 8 |
| 24636402 | 2014 | Elevated levels of autoantibodies targeting the M1 muscarinic acetylcholine receptor and neurofilament medium in sera from subgroups of patients with schizophrenia. | 8 |
| 20201926 | 2010 | Human variation in alcohol response is influenced by variation in neuronal signaling genes. | 52 |
Citation
Dessen P
NEFM (neurofilament medium chain)
Atlas Genet Cytogenet Oncol Haematol. 2017-10-01
Online version: http://atlasgeneticsoncology.org/gene/57073/nefm-(neurofilament-medium-chain)
