Identity
HGNC
LOCATION
22q11.23
LOCUSID
ALIAS
14.1,AGM2,CD179b,IGL1,IGL5,IGLJ14.1,IGLL,IGO,IGVPB,VPREB2
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 3543
MIM: 146770
HGNC: 5870
Ensembl: ENSG00000128322
Variants:
dbSNP: 3543
ClinVar: 3543
TCGA: ENSG00000128322
COSMIC: IGLL1
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000128322 | ENST00000249053 | P15814 |
| ENSG00000128322 | ENST00000330377 | P15814 |
| ENSG00000128322 | ENST00000438703 | C9JEE0 |
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Primary immunodeficiency | KEGG | ko05340 |
| Primary immunodeficiency | KEGG | hsa05340 |
| Hemostasis | REACTOME | R-HSA-109582 |
| Cell surface interactions at the vascular wall | REACTOME | R-HSA-202733 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 27576013 | 2016 | Autosomal recessive agammaglobulinemia associated with an IGLL1 gene missense mutation. | 3 |
| 27611867 | 2016 | The Expression Pattern of the Pre-B Cell Receptor Components Correlates with Cellular Stage and Clinical Outcome in Acute Lymphoblastic Leukemia. | 18 |
| 27576013 | 2016 | Autosomal recessive agammaglobulinemia associated with an IGLL1 gene missense mutation. | 3 |
| 27611867 | 2016 | The Expression Pattern of the Pre-B Cell Receptor Components Correlates with Cellular Stage and Clinical Outcome in Acute Lymphoblastic Leukemia. | 18 |
| 23124203 | 2012 | Structural basis for galectin-1-dependent pre-B cell receptor (pre-BCR) activation. | 22 |
| 23124203 | 2012 | Structural basis for galectin-1-dependent pre-B cell receptor (pre-BCR) activation. | 22 |
Citation
Dessen P
IGLL1 (immunoglobulin lambda like polypeptide 1)
Atlas Genet Cytogenet Oncol Haematol. 2017-10-01
Online version: http://atlasgeneticsoncology.org/gene/57093/igll1-(immunoglobulin-lambda-like-polypeptide-1)
