Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 83743
MIM: 610597
HGNC: 21270
Ensembl: ENSG00000105447
Variants:
dbSNP: 83743
ClinVar: 83743
TCGA: ENSG00000105447
COSMIC: GRWD1
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000105447 | ENST00000253237 | Q9BQ67 |
| ENSG00000105447 | ENST00000598711 | M0QX71 |
Expression (GTEx)
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 34616846 | 2021 | Comprehensive Analysis of Glutamate-Rich WD Repeat-Containing Protein 1 and Its Potential Clinical Significance for Pancancer. | 2 |
| 34933446 | 2021 | GRWD1-WDR5-MLL2 Epigenetic Complex Mediates H3K4me3 Mark and Is Essential for Kaposi's Sarcoma-Associated Herpesvirus-Induced Cellular Transformation. | 2 |
| 34616846 | 2021 | Comprehensive Analysis of Glutamate-Rich WD Repeat-Containing Protein 1 and Its Potential Clinical Significance for Pancancer. | 2 |
| 34933446 | 2021 | GRWD1-WDR5-MLL2 Epigenetic Complex Mediates H3K4me3 Mark and Is Essential for Kaposi's Sarcoma-Associated Herpesvirus-Induced Cellular Transformation. | 2 |
| 31545368 | 2020 | GRWD1 directly interacts with p53 and negatively regulates p53 transcriptional activity. | 5 |
| 31891681 | 2020 | GRWD1 promotes cell proliferation and migration in non-small cell lung cancer by activating the Notch pathway. | 6 |
| 31545368 | 2020 | GRWD1 directly interacts with p53 and negatively regulates p53 transcriptional activity. | 5 |
| 31891681 | 2020 | GRWD1 promotes cell proliferation and migration in non-small cell lung cancer by activating the Notch pathway. | 6 |
| 27856536 | 2017 | GRWD1 negatively regulates p53 via the RPL11-MDM2 pathway and promotes tumorigenesis. | 27 |
| 27856536 | 2017 | GRWD1 negatively regulates p53 via the RPL11-MDM2 pathway and promotes tumorigenesis. | 27 |
| 27552915 | 2016 | Nucleosome assembly and disassembly activity of GRWD1, a novel Cdt1-binding protein that promotes pre-replication complex formation. | 7 |
| 27552915 | 2016 | Nucleosome assembly and disassembly activity of GRWD1, a novel Cdt1-binding protein that promotes pre-replication complex formation. | 7 |
Citation
Dessen P
GRWD1 (glutamate rich WD repeat containing 1)
Atlas Genet Cytogenet Oncol Haematol. 2017-10-01
Online version: http://atlasgeneticsoncology.org/gene/57095/grwd1-(glutamate-rich-wd-repeat-containing-1)
