GPR35 (G protein-coupled receptor 35)

2017-10-01  

Identity

HGNC
LOCATION
2q37.3
LOCUSID
ALIAS
-
FUSION GENES

Other Information

Locus ID:

NCBI: 2859
MIM: 602646
HGNC: 4492
Ensembl: ENSG00000178623

Variants:

dbSNP: 2859
ClinVar: 2859
TCGA: ENSG00000178623
COSMIC: GPR35

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000178623ENST00000319838Q9HC97
ENSG00000178623ENST00000403859Q9HC97
ENSG00000178623ENST00000407714Q9HC97
ENSG00000178623ENST00000430267Q9HC97
ENSG00000178623ENST00000438013Q9HC97

Expression (GTEx)

0
5
10
15
20

Pathways

PathwaySourceExternal ID
Neuroactive ligand-receptor interactionKEGGko04080
Neuroactive ligand-receptor interactionKEGGhsa04080
Signal TransductionREACTOMER-HSA-162582
Signaling by GPCRREACTOMER-HSA-372790
GPCR ligand bindingREACTOMER-HSA-500792
Class A/1 (Rhodopsin-like receptors)REACTOMER-HSA-373076

References

Pubmed IDYearTitleCitations
366371862023Increased GPR35 expression in human colorectal and pancreatic cancer samples: A preliminary clinical validation of a new biomarker.1
372276822023Recent advances in GPR35 pharmacology; 5-HIAA serotonin metabolite becomes a ligand.1
380350842023GPR35 acts a dual role and therapeutic target in inflammation.2
366371862023Increased GPR35 expression in human colorectal and pancreatic cancer samples: A preliminary clinical validation of a new biomarker.1
372276822023Recent advances in GPR35 pharmacology; 5-HIAA serotonin metabolite becomes a ligand.1
380350842023GPR35 acts a dual role and therapeutic target in inflammation.2
352766912022Expression and clinical significance of CXCL17 and GPR35 in endometrial carcinoma.4
356222222022The GPR35 expression pattern is associated with overall survival in male patients with colorectal cancer.1
359260432022Mitochondrial remodeling and ischemic protection by G protein-coupled receptor 35 agonists.33
366140592022Involvement of CXCL17 and GPR35 in Gastric Cancer Initiation and Progression.3
352766912022Expression and clinical significance of CXCL17 and GPR35 in endometrial carcinoma.4
356222222022The GPR35 expression pattern is associated with overall survival in male patients with colorectal cancer.1
359260432022Mitochondrial remodeling and ischemic protection by G protein-coupled receptor 35 agonists.33
366140592022Involvement of CXCL17 and GPR35 in Gastric Cancer Initiation and Progression.3
337242192021Inflammatory bowel disease susceptible gene GPR35 promotes bowel inflammation in mice.4

Citation

Dessen P

GPR35 (G protein-coupled receptor 35)

Atlas Genet Cytogenet Oncol Haematol. 2017-10-01

Online version: http://atlasgeneticsoncology.org/gene/57101/gpr35-(g-protein-coupled-receptor-35)