Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 114294
MIM: 608440
HGNC: 16468
Ensembl: ENSG00000103642
Variants:
dbSNP: 114294
ClinVar: 114294
TCGA: ENSG00000103642
COSMIC: LACTB
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000103642 | ENST00000261893 | P83111 |
| ENSG00000103642 | ENST00000413507 | P83111 |
| ENSG00000103642 | ENST00000557972 | H0YNN5 |
Expression (GTEx)
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38176415 | 2024 | OXCT1 functions as a succinyltransferase, contributing to hepatocellular carcinoma via succinylating LACTB. | 3 |
| 38176415 | 2024 | OXCT1 functions as a succinyltransferase, contributing to hepatocellular carcinoma via succinylating LACTB. | 3 |
| 36282364 | 2023 | LACTB induces cancer cell death through the activation of the intrinsic caspase-independent pathway in breast cancer. | 1 |
| 36375842 | 2023 | LACTB exerts tumor suppressor properties in epithelial ovarian cancer through regulation of Slug. | 0 |
| 37157950 | 2023 | PCBP1 protects bladder cancer cells from mitochondria injury and ferroptosis by inducing LACTB mRNA degradation. | 3 |
| 36282364 | 2023 | LACTB induces cancer cell death through the activation of the intrinsic caspase-independent pathway in breast cancer. | 1 |
| 36375842 | 2023 | LACTB exerts tumor suppressor properties in epithelial ovarian cancer through regulation of Slug. | 0 |
| 37157950 | 2023 | PCBP1 protects bladder cancer cells from mitochondria injury and ferroptosis by inducing LACTB mRNA degradation. | 3 |
| 33259719 | 2022 | Clinical Significance of β-Lactamase Expression in Colorectal Cancer. | 1 |
| 35247327 | 2022 | Structural basis for the catalytic activity of filamentous human serine beta-lactamase-like protein LACTB. | 5 |
| 36088805 | 2022 | LACTB suppresses migration and invasion of glioblastoma via downregulating RHOC/Cofilin signaling pathway. | 4 |
| 36534696 | 2022 | The structure of the human LACTB filament reveals the mechanisms of assembly and membrane binding. | 5 |
| 33259719 | 2022 | Clinical Significance of β-Lactamase Expression in Colorectal Cancer. | 1 |
| 35247327 | 2022 | Structural basis for the catalytic activity of filamentous human serine beta-lactamase-like protein LACTB. | 5 |
| 36088805 | 2022 | LACTB suppresses migration and invasion of glioblastoma via downregulating RHOC/Cofilin signaling pathway. | 4 |
Citation
Dessen P
LACTB (lactamase beta)
Atlas Genet Cytogenet Oncol Haematol. 2017-10-01
Online version: http://atlasgeneticsoncology.org/gene/57106/lactb-(lactamase-beta)
