USP27X (ubiquitin specific peptidase 27 X-linked)

2017-10-01  

Identity

HGNC
LOCATION
Xp11.23
LOCUSID
ALIAS
MRX105,USP22L,USP27

Other Information

Locus ID:

NCBI: 389856
MIM: 300975
HGNC: 13486
Ensembl: ENSG00000273820

Variants:

dbSNP: 389856
ClinVar: 389856
TCGA: ENSG00000273820
COSMIC: USP27X

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000273820ENST00000621775A6NNY8

Expression (GTEx)

0
5
10
15
20
25
30
35
40
45
50

References

Pubmed IDYearTitleCitations
381821612024USP27X variants underlying X-linked intellectual disability disrupt protein function via distinct mechanisms.0
381821612024USP27X variants underlying X-linked intellectual disability disrupt protein function via distinct mechanisms.0
380306042023Phosphorylation of USP27X by GSK3β maintains the stability and oncogenic functions of CBX2.0
380306042023Phosphorylation of USP27X by GSK3β maintains the stability and oncogenic functions of CBX2.0
350185132022Stabilization of SETD3 by deubiquitinase USP27 enhances cell proliferation and hepatocellular carcinoma progression.9
350446322022The deubiquitinase Usp27x as a novel regulator of cFLIP(L) protein expression and sensitizer to death-receptor-induced apoptosis.5
350185132022Stabilization of SETD3 by deubiquitinase USP27 enhances cell proliferation and hepatocellular carcinoma progression.9
350446322022The deubiquitinase Usp27x as a novel regulator of cFLIP(L) protein expression and sensitizer to death-receptor-induced apoptosis.5
320277332020USP27X negatively regulates antiviral signaling by deubiquitinating RIG-I.20
320277332020USP27X negatively regulates antiviral signaling by deubiquitinating RIG-I.20
303410662019TGFβ-Activated USP27X Deubiquitinase Regulates Cell Migration and Chemoresistance via Stabilization of Snail1.55
315340082019Cutting Edge: USP27X Deubiquitinates and Stabilizes the DNA Sensor cGAS to Regulate Cytosolic DNA-Mediated Signaling.32
303410662019TGFβ-Activated USP27X Deubiquitinase Regulates Cell Migration and Chemoresistance via Stabilization of Snail1.55
315340082019Cutting Edge: USP27X Deubiquitinates and Stabilizes the DNA Sensor cGAS to Regulate Cytosolic DNA-Mediated Signaling.32
294971242018USP27-mediated Cyclin E stabilization drives cell cycle progression and hepatocellular tumorigenesis.25

Citation

Dessen P

USP27X (ubiquitin specific peptidase 27 X-linked)

Atlas Genet Cytogenet Oncol Haematol. 2017-10-01

Online version: http://atlasgeneticsoncology.org/gene/57107/usp27x-(ubiquitin-specific-peptidase-27-x-linked)