TM6SF2 (transmembrane 6 superfamily member 2)

2017-10-01  

Identity

HGNC
LOCATION
19p13.11
LOCUSID
ALIAS
-

Other Information

Locus ID:

NCBI: 53345
MIM: 606563
HGNC: 11861
Ensembl: ENSG00000213996

Variants:

dbSNP: 53345
ClinVar: 53345
TCGA: ENSG00000213996
COSMIC: TM6SF2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000213996ENST00000389363Q9BZW4

Expression (GTEx)

0
10
20
30
40
50
60

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
371035562024No association of NAFLD-related polymorphisms in PNPLA3 and TM6SF2 with all-cause and cardiovascular mortality in an Austrian population study.0
384659122024Basic and translational evidence supporting the role of TM6SF2 in VLDL metabolism.0
371035562024No association of NAFLD-related polymorphisms in PNPLA3 and TM6SF2 with all-cause and cardiovascular mortality in an Austrian population study.0
384659122024Basic and translational evidence supporting the role of TM6SF2 in VLDL metabolism.0
364035772023Different effects of low muscle mass on the risk of non-alcoholic fatty liver disease and hepatic fibrosis in a prospective cohort.4
368048322023Association of PNPLA3 (rs738409) & TM6SF2 (rs58542926) and ATG16L1 (rs2241880) genetic variants with susceptibility to hepatocellular carcinoma in a group of Egyptian patients with HCV-induced liver cirrhosis.0
368639292023The impact of transmembrane 6 superfamily 2 (TM6SF2) rs58542926 on liver-related events in patients with advanced chronic liver disease.4
369041122023TM6SF2-rs58542926 Genetic Variant Modifies the Protective Effect of a "Prudent" Dietary Pattern on Serum Triglyceride Levels.2
374007942023Metabolic disorders induced by PNPLA3 and TM6SF2 gene variants affect chronic kidney disease in patients infected with non-genotype 3 hepatitis C virus.1
374954522023Effects of TM6SF2 rs58542926 polymorphism on hepatocellular lipids and insulin resistance in early type 2 diabetes.1
375899142023A study of genetic variants, genetic risk score and DNA methylation of PNPLA3 and TM6SF2 in alcohol liver cirrhosis.0
364035772023Different effects of low muscle mass on the risk of non-alcoholic fatty liver disease and hepatic fibrosis in a prospective cohort.4
368048322023Association of PNPLA3 (rs738409) & TM6SF2 (rs58542926) and ATG16L1 (rs2241880) genetic variants with susceptibility to hepatocellular carcinoma in a group of Egyptian patients with HCV-induced liver cirrhosis.0
368639292023The impact of transmembrane 6 superfamily 2 (TM6SF2) rs58542926 on liver-related events in patients with advanced chronic liver disease.4
369041122023TM6SF2-rs58542926 Genetic Variant Modifies the Protective Effect of a "Prudent" Dietary Pattern on Serum Triglyceride Levels.2

Citation

Dessen P

TM6SF2 (transmembrane 6 superfamily member 2)

Atlas Genet Cytogenet Oncol Haematol. 2017-10-01

Online version: http://atlasgeneticsoncology.org/gene/57136/tm6sf2-(transmembrane-6-superfamily-member-2)