MREG (melanoregulin)

2017-10-01  

Identity

HGNC
MREG
LOCATION
2q35
LOCUSID
55686
ALIAS
DSU,WDT2
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 55686
MIM: 609207
HGNC: 25478
Ensembl: ENSG00000118242

Variants:

dbSNP: 55686
ClinVar: 55686
TCGA: ENSG00000118242
COSMIC: MREG

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000118242ENST00000263268Q8N565
ENSG00000118242ENST00000420348C9JFU1
ENSG00000118242ENST00000424992C9JYV9
ENSG00000118242ENST00000439791C9JAG4
ENSG00000118242ENST00000620139Q8N565

Expression (GTEx)

0
5
10
15
20
25
30
35
40
45
50
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

References

Pubmed IDYearTitleCitations
286981352017MREG suppresses thyroid cancer cell invasion and proliferation by inhibiting Akt-mTOR signaling.6
286981352017MREG suppresses thyroid cancer cell invasion and proliferation by inhibiting Akt-mTOR signaling.6
253012342015The Contribution of Melanoregulin to Microtubule-Associated Protein 1 Light Chain 3 (LC3) Associated Phagocytosis in Retinal Pigment Epithelium.40
253012342015The Contribution of Melanoregulin to Microtubule-Associated Protein 1 Light Chain 3 (LC3) Associated Phagocytosis in Retinal Pigment Epithelium.40
204631772010Multistudy fine mapping of chromosome 2q identifies XRCC5 as a chronic obstructive pulmonary disease susceptibility gene.15
204631772010Multistudy fine mapping of chromosome 2q identifies XRCC5 as a chronic obstructive pulmonary disease susceptibility gene.15

Citation

Dessen P

MREG (melanoregulin)

Atlas Genet Cytogenet Oncol Haematol. 2017-10-01

Online version: http://atlasgeneticsoncology.org/gene/57140/mreg-(melanoregulin)